Title

Correlation between glycemic control and left ventricular diastolic dysfunction in type 2 diabetes

Authors

Aparnna Unnikrishnan Nair¹, Sorabh Sharma², Asma Aara Younus³, Jonathan Roy Varghese⁴, Shanmukha Koppolu⁵ & Sharik Mehraj Patloo^6,*

Affiliation

¹Department of Internal Medicine, Altnagelvin Hospital, Western Health and Social Care Trust, Londonderry, Northern Ireland, UK; ²Department of Internal Medicine, University of Arizona, Tucson, Arizona, USA; ³Department of Infectious Disease, AI Hada Armed Forces Hospital, Taif, KSA, Saudi Arabia; ⁴Department of Internal Medicine, Triunelveli Medical College, Tirunelveli, Tamil Nadu, India; ⁵Department of Trauma and Orthopaedics, Royal London Hospital, Barts NHS Trust, London, England/ UK; ⁶Department of General Internal Medicine, SKIMS Medical College, Srinagar, Jammu Kashmir, India; *Corresponding author

Email

Aparnna Unnikrishnan Nair - E-mail: draparnna02@gmail.com; Phone: +44 7930226479
Sorabh Sharma - E-mail: Sorabh.gmch@gmail.com; Phone: +1 9084050291
Asma Aara Younus - E-mail: asma.airmy11@gmail.com; Phone: +966 509650703
Jonathan Roy Varghese - E-mail: jonathanroy097@gmail.com; Phone: +91 9790935554
Shanmukha Koppolu - E-mail: kshanmukha3@gmail.com; Phone: +44 7448304208
Sharik Mehraj Patloo - E-mail: sharkgroot@gmail.com; Phone: +91 7006575324

Article Type

Research Article

Date

Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025

Abstract

Type 2 diabetes mellitus (T2DM) has been linked to higher cardiovascular morbidity and left ventricular diastolic dysfunction (LVDD). The potential influence of the severity of cardiac dysfunction T2DM patients may depend on diabetes control measures and HbA1c concentration levels. Therefore, it is of interest to determine the relationship between HbA1c and LVDD in patients with type 2 DM by measurement echocardiographic parameters, along diastolic dysfunction and poor glycemic control as indications of the presence of an association. Early cardiac screening interventions may lead to lower long-term cardiovascular morbidity in population studies of poorly controlled diabetic patients.

Keywords

Type 2 diabetes mellitus, glycated hemoglobin, diastolic dysfunction, left ventricular function, echocardiography

Citation

Nair et al. Bioinformation 21(11): 4084-4087 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.