Title

Hydrogen water versus normal saline for post-surgical irrigation: A study on healing and complication rates after third molar extraction

Authors

Harshini Devi¹, S. P. Indra Kumar^2,*, Narendar Ramesh³, S.U Arrvinthan⁴, R. S. Asok Kumar⁴, Sarmatha Selvaraj⁵

Affiliation

¹Department of Oral and Maxillofacial Surgery, Vivekanandha Dental college for Women, Tiruchengode, Namakkal District, Tamil Nadu, India; ²Department of Oral and Maxillofacial Surgery, Vivekanandha Dental college for Women, Tiruchengode, Namakkal District, Tamil Nadu, India; ³Department of Oral and Maxillofacial Surgery, Vivekanandha Dental college for Women, Tiruchengode, Namakkal District, Tamil Nadu, India; ⁴Department of Oral and Maxillofacial Surgery, Vivekanandha Dental college for Women, Tiruchengode, Namakkal District, Tamil Nadu, India; ⁵Department of Periodontology, Adhiparasakthi Dental college and Hospital, Melmaruvathur, Tamil Nadu, India; *Corresponding author

Email

Harshini Devi - E-mail: kumarjeeth@yahoo.com
S. P. Indra Kumar - E-mail: drspindrakumar@vdcw.ac.in
Narendar Ramesh - E-mail: drrnarendar@vdcw.ac.in
S.U Arrvinthan - E-mail: su.arrvinthan1996@gmail.com
R. S. Asok Kumar - E-mail: drrsasokkumar@vdcw.ac.in
Sarmatha Selvaraj - E-mail: sarmathaselvaraj6@gmail.com

Article Type

Research Article

Date

Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025

Abstract

Oral surgery involving impacted mandibular third molars is a common procedure. However, it results in postoperative complaints such as pain, swelling, trismus and dry socket. Therefore, it is of interest to compare hydrogen water and normal saline as surgical irrigants in patients undergoing third molar removal. The study included 30 patients total who were divided into 2 groups of 15 and clinical parameters were assessed post-operative days 1, 2 and 7. Results showed all patients improved over time and that patients in the hydrogen water group had significantly greater improvements in pain, swelling and trismus, as well as a lower incidence of dry socket from postoperative day 2 onward. The anti-inflammatory and antibacterial properties of hydrogen water appear to make it a better irrigant agent than normal saline in healing and reducing postoperative complications.

Keywords

Hydrogen water, dry socket, infection, mandibular third molar, normal saline, pain, trismus

Citation

Devi et al. Bioinformation 21(11): 4148-4152 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.