Title
Effect of propolis extract and chlorhexidine in treating chronic periodontitis: A randomized controlled trial
Authors
Darshana Digambar Shivatare, Vidya Dodwad*, Nishita Bhosale, Devashri Newaskar, Manasi Yewale & Roopal Gupta
Affiliation
Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, Maharashtra, India; *Corresponding author
Darshana Digambar Shivatare - E-mail: darshanaaaaa1598@gmail.com
Vidya Dodwad - E-mail: vidyadodwad@yahoo.com
Nishita Bhosale - E-mail: Nishita.bhosale@bharatividyapeeth.edu
Devashri Newaskar - E-mail: devashri.newaskar@bharatividyapeeth.edu
Manasi Yewale - E-mail: manasi.yewale@bharatividyapeeth.edu
Roopal Gupta - E-mail: roopalgupta170298@gmail.com
Article Type
Research Article
Date
Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025
Abstract
Chronic periodontitis remains a significant dental health issue, with current treatments often relying on chemical irrigants like chlorhexidine, which may have limitations. Therefore, it is of interest to compare the clinical and microbiological effects of 0.2% chlorhexidine (CHX) and 25% propolis extract as subgingival irrigants adjunctive to scaling and root planing in chronic periodontitis patients. Twenty patients were randomly assigned to receive either CHX or propolis following SRP. Significant improvements were observed in clinical parameters (Gingival Index, Plaque Index and Probing Pocket Depth) and microbiological reduction in both groups, with propolis showing superior results. Propolis extract exhibited greater efficacy in reducing clinical symptoms and bacterial detection, suggesting it as a promising natural alternative to CHX.
Keywords
Chronic periodontitis, scaling and root planing, chlorhexidine, propolis, subgingival irrigation, local drug delivery
Citation
Shivatare et al. Bioinformation 21(11): 4179-4184 (2025)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
