Title
Serum calcium and magnesium in preeclampsia: A comparative study
Authors
Himanshy Rai1, Shweta Yadav1, Shambhavi Soni1, Pratiksha Yadav1, Meghna Singh Jadon2 & Mayank Pratap Singh1,*
Affiliation
1Department of Obstetrics and Gynaecology, Government Medical College, Datia, Madhya Pradesh, India; 2Department of Public Health, Datta Meghe Institute of Higher Education and Research Deemed to be University, Wardha, Maharashtra, India; *Corresponding author
Himanshy Rai - E-mail: Raihimanshy@gmail.com
Shweta Yadav - E-mail: Shweta.6279@gmail.com
Shambhavi Soni - E-mail: drshambhavisoni@gmail.com
Pratiksha Yadav - E-mail: drpratikshayadavjhansi@gmail.com
Meghna Singh Jadon - E-mail: drmeghnasinghjadon@gmail.com
Mayank Pratap Singh - E-mail: mayanksingh686@gmail.com
Article Type
Research Article
Date
Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025
Abstract
Preeclampsia is a hypertensive disorder of pregnancy linked to endothelial dysfunction and electrolyte imbalance. Therefore, it is of interest to evaluate serum calcium and magnesium levels in 100 preeclamptic and 100 normotensive pregnant women beyond 28 weeks gestation at a tertiary hospital in Central India. Spectrophotometric analysis showed significantly lower calcium (7.84 ± 0.74 mg/dL vs. 9.68 ± 0.97 mg/dL; p<0.001) and magnesium levels (1.74 ± 0.54 mg/dL vs. 1.88 ± 0.76 mg/dL; p=0.040) in preeclamptic women. Adverse outcomes such as preterm birth, cesarean delivery, and NICU admissions were more frequent in the preeclampsia group. These findings suggest the utility of calcium and magnesium screening in antenatal care for early risk stratification and potential prevention of complications.
Keywords
Preeclampsia, serum calcium, serum magnesium, pregnancy-induced hypertension, maternal outcomes, fetal outcomes
Citation
Rai et al. Bioinformation 21(11): 4222-4225 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
