Title
Comparative analysis of general anaesthesia with and without dexmedetomidine in emergence agitation
Authors
Shalini Jain, KP Rasna*, Mohan Babu Nema & Manish Banjare
Affiliation
Department of Anaesthesia, MGM Medical College, Indore, Madhya Pradesh, India; *Corresponding author
Shalini Jain - E-mail: drshalininjain@gmail.com
KP Rasna - E-mail: Rasnakp6@gmail.com
Mohan Babu Nema - E-mail: mohannema718@gmail.com
Manish Banjare - E-mail: manish-banjare@yahoo.co.in
Article Type
Research Article
Date
Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025
Abstract
Emergence agitation (EA) is a common concern in maxillofacial surgeries under general anaesthesia. Therefore, it is of interest to evaluate the role of intraoperative dexmedetomidine infusion in its prevention. Ninety ASA I–II adult patients were randomized into two groups general anaesthesia alone (Group A) and general anaesthesia with dexmedetomidine (Group B). Dexmedetomidine significantly reduced the incidence and severity of EA (p < 0.001) improved sedation scores and provided better hemodynamic stability without increasing pain, nausea or vomiting. Bradycardia was more frequent in the dexmedetomidine group but also manageable making it a safe and effective adjuvant for enhancing recovery quality.
Keywords
Dexmedetomidine, emergence agitation, general anaesthesia, maxillofacial surgery, sedation, hemodynamic stability
Citation
Jain et al. Bioinformation 21(11): 4231-4235 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
