Title

Linking pulmonary function with rheumatoid arthritis

Authors

Rahul Soni¹, Pankaj Kumar Gupta², Yasha Bandil³, Ritu Rani Vinodia^4,* & Sachin Parmar⁵

Affiliation

¹Department of Pulmonary Medicine, BirsaMunda Government Medical College, Shahdol, Madhya Pradesh, India; ²Departmentof General Medicine, BirsaMunda Government Medical College, Shahdol, Madhya Pradesh, India; ³Department of Ophthalmology, BirsaMunda Government Medical College, Shahdol, Madhya Pradesh, India; ⁴Department of ENT, BirsaMunda Government Medical College, Shahdol, Madhya Pradesh, India; ⁵Department of Community Medicine, V.K.S.Govt. Medical College, Neemuch, Madhya Pradesh, India; *Corresponding author

Email

Rahul Soni - E-mail: Rssonirahul@gmail.com
Yasha Bandil - E-mail: yashabandil@gmail.com
Pankaj Kumar Gupta - E-mail: dr.pankajgupta89@gmail.com
Ritu Rani Vinodia- E-mail: rituvinodia@gmail.com
Sachin Parmar - E-mail: dr.sachinparmar@gmail.com

Article Type

Research Article

Date

Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that frequently leads to pulmonary involvement, contributing to morbidity and mortality. Therefore, it is of interest to assess pulmonary function in 100 participants (50 RA patients and 50 controls) using spirometry. RA patients showed significantly higher odds of pulmonary function test (PFT) abnormalities, including FVC%, FEV1%, PEFR% and FEF 25–75%. A higher disease severity, longer disease duration and elevated serological markers (RF, ACPA, CRP) were strongly associated with these abnormalities. Routine spirometry should be incorporated into RA management for early detection and improved outcomes.

Keywords

Rheumatoid arthritis, pulmonary function tests, restrictive lung disease

Citation

Soni et al. Bioinformation 21(12): 4285-4288 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.