Title

Integrative management of chronic kidney disease: A case study combining siddha and modern medicine

Authors

Senthan Tamilselvana^1,*, Varshini Kumar², Mariappan Andic¹ & Radha Sudalaimanid³

Affiliation

¹Department of Gunapadam, National Institute of Siddha, Affiliated to the Tamil Nadu Dr. MGR Medical University, Chennai-47, Tamil Nadu, India; ²Department of Noi Naadal, National Institute of Siddha, Affiliated to the Tamil Nadu Dr. MGR Medical University, Chennai-47, Tamil Nadu, India; ³Siddha Government Primary Health Center, Agastheeswaram, Tamil Nadu, India; *Corresponding author

Email

Senthan Tamilselvana - E-mail: senthansiddha@gmail.com
Varshini Kumar - E-mail: varshini98kumar@gmail.com
Mariappan Andic - E-mail: mariappannis@gmail.com
Radha Sudalaimanid - E-mail: drradha165@gmail.com

Article Type

Views

Date

Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025

Abstract

Chronic kidney disease (CKD) is a progressive disorder frequently associated with long standing Type 2 Diabetes Mellitus (DM) and Systemic Hypertension (SHTN). A 53-year-old male with an 8-year history of DM and a 5-year history of SHTN presented with pedal edema, frothy urination, dyspnoea and generalized itching, with no improvement from allopathic treatment and he refused dialysis. He opted for Siddha medicine, receiving Polyherbal nephroprotective decoction, polyherbal iron enriched decoction, calcined pearl-based formulation and calcined Herbo mineral formulation, while continuing Metformin and Amlodipine. After two and a half months, the patient showed significant clinical and biochemical improvements, including reduced serum creatinine, resolution of edema and relief from urinary and respiratory symptoms. Thus, we show the potential of Siddha medicine as a nephroprotective and integrative approach in managing CKD alongside allopathic treatment.

Keywords

Chronic kidney disease, siddha, integrative medicine, nephroprotective, renal fluid retention disorder (Neeradaipu Noi)

Citation

Tamilselvana et al. Bioinformation 21(12): 4344-4349 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.