Title
Effect of sleep deprivation and stress on periodontal disease: A clinico-biochemical study
Authors
Pratisha Rahulkar1,*, Laxman Boyapati1, Abhigna Parikipandla1, Aravind Kumar1, M.V. Devarathnamma2, V Pramod1 & Miral Mehta3
Affiliation
1Department of Periodontology, Meghna Institute of Dental Sciences, Nizamabad, Telangana, India; 2Department of Dental surgery, Private Practitioner, Nizamabad, Telangana, India; 3Department of Pediatric and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India; *Corresponding author
Pratisha Rahulkar - E-mail: pratishathandle@gmail.com
Laxman Boyapati - E-mail: boyapatilaxman@gmail.com
Abhigna Parikipandla - E-mail: pabhigna1995@gmail.com
Aravind Kumar - E-mail: dr.aravindkumar.smile@gmail.com
M.V Devarathnamma - E-mail: mvdevarathna@yahoo.co.in
V Pramod - E-mail: Pramdm@gmail.com
Miral Mehta - E-mail: miral9829@gmail.com
Article Type
Research Article
Date
Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025
Abstract
Chronic stress and poor sleep are important lifestyle factors influencing that can influence the onset and progression of periodontal disease. Hence, a clinical biochemical study was conducted on 30 participants aged 25-50 years at Meghna Institute of Dental Sciences. Subjects were divided into three groups and FMBS, FMPS, PPD, CAL were recorded. Stress was measured using the 10-item Perceived Stress Scale (IPSS-10) and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). It is found that periodontal disease is associated with stress, sleep deprivation and clinical indices such as CAL and PPD, while serum cortisol levels exhibited minimal variation across groups; the interplay of lifestyle factors highlights the need for a holistic approach to periodontal care.
Keywords
Sleep deprivation, stress, periodontal disease, biochemical assessment, clinical evaluation
Citation
Rahulkar et al. Bioinformation 21(12): 4459-4463 (2025)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
