Title
A clinical study to evaluate meibomian gland dysfunction and tear film changes in patients with pterygium
Authors
Neda Rahman, Sunil Kumar*, Rohit Kumar Mahato, Deepankar Deepankar & Mousmi Anand
Affiliation
Regional Institute of Ophthalmology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India; *Corresponding author
Neda Rahman - E-mail: nedarahman7@gmail.com
Sunil Kumar - E-mail: drsunilpgi12@yahoo.com
Rohit Kumar Mahato - E-mail: rohitmahato9@gmail.com
Deepankar Deepankar - E-mail: deepsunny100@gmail.com
Mousmi Anand - E-mail: mousmi.anand07@gmail.com
Article Type
Research Article
Date
Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025
Abstract
Pterygium is a degenerative ocular surface disorder whose relationship with meibomian gland dysfunction (MGD) and tear film instability remains understudied, especially in Eastern India. This case-control study included 110 adults to evaluate tear film parameters and MGD status in pterygium patients compared with healthy controls. Pterygium cases showed significantly higher rates of Schirmer's I, TBUT and TMH abnormalities, with strong correlations between tear instability and MGD severity. Higher pterygium grades demonstrated the most marked tear film disruption and meibomian gland changes. Thus, we show the need for early detection and management of MGD and dry eye to improve outcomes in pterygium patients.
Keywords
Pterygium, meibomian gland dysfunction, tear film, dry eye, ocular surface disease, tear film break-up time, schirmer's test
Citation
Rahman et al. Bioinformation 21(12): 4504-4509 (2025)
Edited by
Hiroj Bagde
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
