Title
Residual monomer release from different acrylic-based dental materials: An in vivo evaluation
Authors
Anil Kumar Venkeshwarlu James*1, Vivek Narra2, Kalyana Ponangi3, Sheeba Glory Chowdary4, T Mahesh Tagore5 & Hardik Dholakia6
Affiliation
1Department of Jefferson Dental & Orthodontics, 907 S WW White RD, San Antonio, Texas, USA; 2General Dentist, Familia Dental, Springfield Illinois, USA; 3General dentist, Noble Dental Community Clinics, Wautoma, Wisconsin, USA; 4University of Texas San Antanio School of Dentistry, Texas, USA; 5Department of Oral & Maxillofacial Pathology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India; 6Thundermist health centre, Woonsocket, USA; *Corresponding author
Anil Kumar Venkeshwarlu James - E-mail: vj.anilkumar.mds@gmail.com
Vivek Narra - E-mail: Viveknarra@gmail.com
Kalyana Ponangi - E-mail: Kalyan.ponangi@gmail.com
Sheeba Glory Chowdary - E-mail:drsgc.mds@gmail.com
T Mahesh Tagore - E-mail: dr.mahesh.tagore@gmail.com
Hardik Dholakia - E-mail: hardikdholakiya90@gmail.com
Article Type
Research Article
Date
Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025
Abstract
Primary concern from residual monomer and other leachable components from denture base resins is allergic and sensitivity reactions among patients. Therefore, it is of interest to evaluate the leaching ability of residual methylmethacrylate monomer from heat polymerising acrylic, auto polymerising acrylic, auto polymerising acrylic cured under pot pressure, and thermoformed sheets in 40 children aged 7–14 years. Saliva samples were collected at 5 minutes, 1 hour, 24 hours, and 1 month after appliance insertion and analyzed by High Performance Liquid Chromatography. Results revealed significantly higher monomer release from auto polymerising acrylic materials, followed by heat cure, while thermoformed sheets showed no detectable release. The findings indicate thermoformed sheets are safer and more clinically acceptable alternatives for pediatric appliances.
Keywords
Methylmethacrylate, acrylic resins, thermoformed sheets, leachability, HPLC
Citation
James et al. Bioinformation 21(12): 4595-4598 (2025)
Edited by
Rashmi Daga
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
