Title

The application of MTA in single-visit apexification treatment: A prospective study

Authors

S.K Mahboob Rahaman^1,*, Sagolsem Chandarani², Anuradha Mukherjee¹, Thara Elizabeth Jes³, Prantika Mandal¹ & Abhijeet Buragohain⁴

Affiliation

¹Department of Conservative Dentistry and Endodontics, North Bengal Dental College and Hospital, Darjeeling, West Bengal, India; ²Department of Conservative Dentistry and Endodontics, Regional Institute of Medical Sciences , Imphal, Manipur, India; Bengal, India; ³Department of Conservative Dentistry and Endodontics, Hazaribag College of Dental Sciences and Hospital, Hazaribag Jharkhand, India; ⁴Department of Dentistry, Assam Medical College and Hospital, Dibrugarh, Assam, India; *Corresponding author

Email

S.K Mahboob Rahaman - E-mail: rskmahboob@gmail.com

Sagolsem Chandarani - E-mail: chandasagolsem@gmail.com

Anuradha Mukherjee - E-mail: mamendo2017@gmail.com

Thara Elizabeth Jes - E-mail: tharaelizabethjes@gmail.com

Prantika Mandal - E-mail: anannapr14@gmail.com

Abhijeet Buragohain - E-mail: drabhijeet10@gmail.com

Article Type

Research Article

Date

Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025

Abstract

Apexification is a treatment procedure used to induce a calcified barrier at the apex of an immature tooth with an open root canal, often as a result of pulpal necrosis or trauma. Hence, this prospective study evaluates the clinical efficacy of mineral trioxide aggregate (MTA) in achieving apexification in a cohort of 85 patients with immature, non-vital teeth. A total of 85 patients with immature permanent teeth requiring apexification were enrolled in this prospective clinical study. Each patient underwent a one-visit apexification procedure using MTA as the apical barrier material. Radiographic analysis showed the formation of a calcified barrier in most cases. Thus, one-visit apexification using MTA is an effective and efficient technique for managing immature, non-vital teeth.

Keywords

Apexification, endodontic procedure, immature teeth, MTA, periapical inflammation

Citation

Rahaman et al. Bioinformation 21(12): 4741-4745 (2025)

Edited by

Rashmi Daga

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.