Title
Evaluation of salivary pH and buffering capacity in gastroesophageal reflux among patients with dental erosion
Authors
Shweta V. Sagare1, Jasmine Marwaha2,*, Vidya Nagabhushan3, Deepankar Dass4, Mohd Ahmed Ali khan5 & Roger Biswal6
Affiliation
1Department of Conservative Dentistry and Endodontics, Bharati Vidyapeeth (Deemed To Be University) Dental College and Hospital Sangli, Maharashtra, India; 2Department of Conservative dentistry and Endodontics, National Dental College and Hospital, Derabassi,140507, India; 3Oral Pathologist, Pandits dental care, LIC colony srirampura 2nd Stage, Mysore-570023, Karnataka, India; 4Department of Conservative Dentistry & Endodontics, Maharshi Markendshwar College of Dental Sciences & Research, Mullana, Haryana, India; 5Department of Conservative dentistry and endodontics, Rungta college of dental science and research, Chattisgarh;6Department of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, KIIT Deemed To Be University, Patia, Bhubaneswar, Odisha, India; *Corresponding author
Shweta V. Sagare - E-mail: shwetasagare@gmail.com
Jasmine Marwaha - E-mail: drjasminemarwaha@gmail.com
Vidya Nagabhushan - E-mail: drvidya.aradhya@gmail.com
Deepankar Dass- E-mail: deepankardass87@gmail.com
Mohd Ahmed Ali khan - E-mail: alikhan3548@gmail.com
Roger Biswal - E-mail: biswalroger@gmail.com
Article Type
Research Article
Date
Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025
Abstract
Gastroesophageal reflux disease (GERD) places the mouth tissues under the acidic effects of the gastrointestinal secretions, which may affect the protective effects of salivation and increase the susceptibility of the dentures. Therefore, it is of interest to compare salivary pH, buffering capacity and dental erosion among 45 GERD patients and 45 controls. The patients with GERD demonstrated a large reduction in salivary PH and buffering capacity, and dental erosion was much more prevalent. The salivary parameters were found to be negatively correlated with the erosion severity. The impact of GERD-related changes in saliva is a significant factor in the case of dental erosion, which justifies the significance of interdisciplinary prevention and management approaches.
Keywords
Gastroesophageal reflux disease; salivary pH; buffering capacity; dental erosion; tooth wear; saliva; BEWE index
Citation
Sagare et al. Bioinformation 21(12): 4842-4848 (2025)
Edited by
by Hiroj Bagde
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
