Title

Evaluation of soft and hard tissue responses to dental implants placed with and without platelet-rich fibrin

Authors

Mohammed Ahsan Razi^1,*, Parveen Ranga², Rakhi Kumari¹, Amit Kumar³, Ria Sahay¹ & Sharmila Kumari⁴

Affiliation

¹Department of Periodontology, Hazaribag College of Dental Sciences & Hospital, Hazaribag, Jharkhand, India; ²Department of Dentistry, Adesh Medical College and Hospital Shahabad Markanda, Kurukshetra, Haryana, India; ³Department of Dentistry, Desh Bhagat University, Mandi Gobindgarh, Punjab, India; ⁴Department of Periodontology, Dental institute, RIMS, Ranchi, Jharkhand, India; *Corresponding author

Email

Mohammed Ahsan Razi - E-mail: mahsan0708@gmail.com
Parveen Ranga - E-mail: dr.parveenranga@gmail.com
Rakhi Kumari - E-mail: mahtorakhi94@gmail.com
Amit Kumar - E-mail: dramitramku@gmail.com
Ria Sahay - E-mail: riasahay2015@gmail.com
Sharmila Kumari - E-mail: shreedentist@gmail.com

Article Type

Research Article

Date

Received November 15, 2025; Revised December 15, 2025; Accepted December 15, 2025, Published December 15, 2025

Abstract

The challenge of enhancing soft and hard tissue healing during dental implant procedures, particularly in terms of preventing implant failure and improving tissue regeneration, which is explored through the use of Platelet-Rich Fibrin (PRF). The study population consisted of 60 randomly selected participants receiving either treatment with PRF or without PRF. The clinical and radiographic data were compiled at Baseline, 1, 3 and 6 months post-operative period respectively. Results show PRF positively impacts on the health of the gingiva preserve bone levels and improve survival rates of the implant. Thus, we show the understanding of Platelet-Rich Fibrin (PRF) as an adjunct in dental implant procedures, highlighting its positive impact on both soft and hard tissue healing, which may improve clinical outcomes, including gingival health, bone preservation and implant success rates.

Keywords

Bone density, gingival health, implant survival, Platelet-rich fibrin, soft tissue healing

Citation

Razi et al. Bioinformation 21(12): 5006-5010 (2025)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.