Title
Genetic polymorphisms in cardiovascular disease susceptibility among different ethnic groups
Authors
Promila Chauhan1*, Hemali Jha2 & Amrit Podder3
Affiliation
1Department of Physiology, Santosh Medical College (Deemed University), Ghaziabad, Uttar Pradesh, India; 2Department of Internal Medicine, Integral Institute of Medical Sciences and Research, Integral University, Lucknow, Uttar Pradesh, India; 3Department of Physiology, Teerthanker Mahaveer Medical College & Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India; *Corresponding author
Promila Chauhan - E-mail:
drpchauhan1@gmail.com
Hemali Jha - E-mail: dr_hemali@yahoo.co.in
Amrit Podder - E-mail: amritpodder0@gmail.com
Article Type
Research Article
Date
Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026
Abstract
Genetic polymorphisms in cardiovascular disease (CVD) susceptibility across different ethnic groups is highly imperetive. Therefore, it is of interest to investigate the role of genetic polymorphisms in cardiovascular disease (CVD) susceptibility across different ethnic groups. Participants were tested for variations in LDLR, APOE and LPL genes and their association with cardiovascular risk factors such as cholesterol levels and blood pressure was examined. Data shows ethnic differences in the prevalence of these polymorphisms, suggesting that genetic factors contribute to CVD risk in a population-specific manner. Thus, we show the need for personalized cardiovascular risk assessment strategies. The ethnic-specific distribution of genetic polymorphisms (LDLR, APOE and LPL) linked to cardiovascular disease susceptibility, highlighting the need for personalized cardiovascular risk assessment strategies based on genetic and ethnic factors is highlighted.
Keywords
APOE, cardiovascular disease, ethnic groups, low-density lipoprotein receptor (LDLR), polymorphisms
Citation
Chauhan et al. Bioinformation 22(1): 38-41 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
