Title

Sarcopenia with postoperative outcomes in patients undergoing pancreaticoduodenectomy

Authors

Nisha B Jain¹, Javid Ahmad Peer², Ishfaq Ahmad Gilkar³*, Anil Mehta⁴, Varun Dogra⁵, Umer Mushtaq² & Seema Gafurjiwala⁵

Affiliation

¹Department of Surgery, SKS Hospital Medical College and Research Centre, Mathura, Sir gangaram Hospital, New Delhi, India; ²Department of Surgical Gastroenterology, Gangaram Hospital, Delhi, India; ³Department of Surgical Oncology, Sher-i-Kashmir Institute of Medical Sciences, Jammu, India; ⁴Department of General Surgery, AIIMS, Jammu, India; ⁵Department of Statistics, The Indian Institute of Public Health, Hyderabad, India; *Corresponding author

Email

Nisha B Jain - E-mail: nishabjain1811@gmail.com
Javid Ahmad Peer - E-mail: drjavid16@gmail.com
Ishfaq Ahmad Gilkar - E-mail: drishfaqahmadgilkar@gmail.com
Anil Mehta - E-mail: Anilmehta665@gmail.com
Varun Dogra - E-mail: drdogravarun@gmail.com
Seema Gafurjiwala - E-mail: seema.m@iiphh.org

Article Type

Research Article

Date

Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026

Abstract

The prevalence of sarcopenia in patients undergoing pancreaticoduodenectomy (PD) for pancreatic and periampullary tumors and its impact on postoperative outcomes is highly relevant. Therefore, it is of interest to investigate the prevalence of sarcopenia in patients undergoing pancreaticoduodenectomy (PD) for pancreatic and periampullary tumors. A prospective observational analysis of 50 patients revealed that sarcopenia, assessed through Psoas Muscle Index, Hand Grip Strength and Gait Speed, is a significant predictor of postoperative outcomes. Age did not notably affect sarcopenia prevalence, while factors such as gender, ECOG status and diabetes were identified as key risk factors. Gait speed was found to be the strongest predictor of mortality, emphasizing its potential as a primary diagnostic tool. The identification of sarcopenia as a significant predictor of postoperative outcomes in pancreaticoduodenectomy patients with gait speed emerging as the strongest predictor of mortality, offering a potential tool for preoperative assessment and improved patient management.

Keywords

Pancreatic cancer, Sarcopenia, body mass index

Citation

Jain et al. Bioinformation 22(1): 66-70 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.