Title
Clinical-histopathologic features in oral lichen planus and lichenoid lesions: A comparative analysis
Authors
Navneet Singh Kathuria1, Gagandeep Kaur Sidhu1, Navdeep Singh Kathuria2,*, Amandeep Kaur3 & Rahul Sharma4
Affiliation
1Department of Oral Pathology, Dr S.S. Tantia Dental College, Hospital and Research Centre, Sriganganagar, Rajasthan, India; 2Department of General Medicine, Dr S.S. Tantia Dental College, Hospital and Research Centre, Sriganganagar, Rajasthan, India; 3Department of Conservative and Endodontics, Dr S.S. Tantia Dental College, Hospital and Research Centre, Sriganganagar, Rajasthan, India; 4Department of Oral and Maxillofacial Surgery, Dr S.S. Tantia Dental College, Hospital and Research Centre, Sriganganagar, Rajasthan, India; *Corresponding author
Navneet Singh Kathuria - E-mail: dr.navneet00@gmail.com
Gagandeep Kaur Sidhu - E-mail: dr.gagansidhu14@gmail.com
Navdeep Singh Kathuria - E-mail: mk4725@gmail.com
Amandeep Kaur - E-mail: amandholksp@gmail.com
Rahul Sharma - E-mail: rahulmaxfax@yahoo.co.in
Article Type
Research Article
Date
Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026
Abstract
The clinical and histopathological distinctions between oral lichen planus (OLP) and oral lichenoid lesions (OLLs) are clinically and histopathologically difficult since they both have overlapping clinical presentations. The retrospective cross-sectional study involved the assessment of 100 biopsy-proven cases to determine discriminating clinical patterns and microscopic characteristics. OLP were significantly more bilateral and had a typical band-like superficial lymphocytic infiltrate with OLLs having recognisable triggers, more inflammation around vessels and frequent eosinophils. These histopathologic clues had high levels of discriminatory power between the two entities. A combination of clinical and major microscopic markers, i.e., eosinophil-rich infiltrates has a great impact on diagnostic accuracy between OLP and OLL.
Keywords
Oral lichen planus, oral lichenoid lesions, histopathology, diagnosis, eosinophils, oral pathology
Citation
Kathuria et al. Bioinformation 22(1): 192-196 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
