Title
Effect of diode laser on self-assembling peptide enamel remineralization - In vitro study
Authors
V.S. Pratheek*
Affiliation
Department of Conservative Dentistry and Endodontics, Government Dental College Alappuzha, Vandanam, Kerala, India; *Corresponding author
V.S. Pratheek - E-mail: vs.pratheek@gmail.com
Article Type
Research Article
Date
Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026
Abstract
The caries lesions of early enamel caries do not have effective non-invasive treatment modalities and thus it is necessary to research on whether the adjunctive diode laser therapy can increase the ability of self-assembled peptide (SAP) biomaterials in remineralization. Eighty premolars had been extracted and randomly separated into four groups (n= 20 each): the control group (artificial saliva), Group B (SAP), Group C (diode laser), and Group D (SAP + diode laser). The process of remineralization lasted 7 days, and the microhardness of surfaces was tested. SAP (P11-4) was very effective on remineralizing the demineralized enamel than the control, whereas diode laser was relatively ineffective. The diode laser used with SAP had synergies with high enamel microhardness recovery. Thus, we show that the use of diode laser can be an effective adjunct in management of early caries through the use of biomimetic remineralizing agents in non-invasive.
Keywords
Dental caries, enamel remineralization, self-assembling peptide, P11-4, diode laser, microhardness
Citation
Pratheek, Bioinformation 22(1): 256-259 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
