Title

Role of endocervical curettage during colposcopy for women with abnormal cervical screening results in predicting cervical intraepithelial neoplasia

Authors

Latifa Akhter¹,*, Tahsin Tabassum², Mehriban Amatullah3, Walida Afrin³, Farzana Nasrin¹, Kashfia Binte Quasem¹, Rebeka Sultana¹ & Halima Khanam¹

Affiliation

¹Department of Gynaecological Oncology, Bangladesh Medical University (BMU), Dhaka, Bangladesh; ²Department of Medicine, Chittagong Medical College Hospital, Chittagong, Bangladesh; ³Department of Obstetrics and Gynecology, Bangladesh Medical University, Dhaka, Bangladesh; *Corresponding author

Email

Latifa Akhter - E-mail: latifaakhterd@yahoo.com

Tahsin Tabassum - E-mail: tahsin.fabi@gmail.com

Mehriban Amatullah - E-mail: amatullah.mehriban@gmail.com

Walida Afrin - E-mail: walidaafrin@gmail.com

Farzana Nasrin - E-mail: farzananasrin81@yahoo.com

Kashfia Binte Quasem - E-mail: kashfia.jubaid@gmail.com

Rebeka Sultana - E-mail: rebeka9891@gmail.com

Halima Khanam - E-mail: taiyeebchowdhury@gmail.com

Article Type

Research Article

Date

Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026

Abstract

The problem of accurately predicting high-grade cervical intraepithelial neoplasia (CIN 2+) in women with positive screening tests remains a challenge in clinical practice. Therefore, it is of interest to evaluate the role of endocervical curettage (ECC) in predicting high-grade cervical intraepithelial neoplasia (CIN 2+) in women with positive screening tests. Conducted at Bangabandhu Sheikh Mujib Medical University, the study included 112 women aged 30-60 with abnormal Pap smears or VIA-positive results. While colposcopy-directed biopsy (CDB) detected 23.2% of CIN 2+ cases, ECC in combination with CDB identified 35.7%. Data shows that ECC to enhance detection but with lower sensitivity (38.5%) and positive predictive value (41.7%) compared to biopsy alone. ECC proved beneficial in improving CIN 2+ detection in high-risk groups

Keywords

Cervical intraepithelial neoplasia (CIN), Colposcopy-directed biopsy (CDB), Endocervical curettage (ECC), endocervical curettage, colposcopy, CIN 2+, cervical cancer, gynecological oncology

Citation

Akhter et al. Bioinformation 22(1): 418-424 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.