Title
Clinical evaluation of open flap debridement with or without EmdogainŽ in treating intrabony defects
Authors
Simrita Singh, Vandana Sarangal, Sahib Tej Singh*, Vidhuta Sareen, Simranjit Kaur & Sakshi Verma
Affiliation
Department of Periodontology, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India; *Corresponding author
Simrita Singh - E-mail:
simritasingh2014@gmail.com
Vandana Sarangal - E-mail: drvandana6@gmail.com
Sahib Tej Singh - E-mail: sahibtejsingh@yahoo.com
Vidhuta Sareen - E-mail: drvidhutasareen@gmail.com
Simranjit Kaur - E-mail: dr.simrank26@gmail.com
Article Type
Research Article
Date
Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026
Abstract
Periodontitis causes intrabony defects and while open flap debridement (OFD) with EMD and GTR shows promise, the comparative effectiveness of EMD in treating these defects remains underexplored. Open flap debridement (OFD) or access flap surgery is used in conjunction with biological factors such as enamel matrix derivative (EMD) and regenerative techniques involving guided tissue regeneration (GTR) in order to overcome these intrabony defects. In numerous clinical investigations, the application of EMD has demonstrated notable clinical improvements in bone fill clinical attachment gain and pocket depth reduction. Thus, the clinical effectiveness of open flap debridement with and without enamel matrix derivative (EMD) in treating periodontal intrabony defects, further exploring EMD's contribution to clinical outcomes such as bone fill, attachment gain and pocket depth reduction is reported.
Keywords
Open flap debridement, Enamel matrix derivative (EMD), periodontal intrabony defects, Regenerative techniques, Clinical attachment gain
Citation
Singh et al. Bioinformation 22(1): 430-435 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
