Title
Transient neuropsychiatric events after HPV vaccination among adolescent schoolgirls in India
Authors
Raj Kamal Choudhary*, Obaid Ali & Rakhshanda Khatoon
Affiliation
Department of Medicine, Jawaharlal Nehru Medical College, Bhagalpur, India; *Corresponding author
Raj Kamal Choudhary -E-mail:
choudhary.drrajkamal@gmail.com; Phone: +91 9431214880
Obaid Ali -E-mail: obaid.ali62@gmail.com
Rakhshanda Khatoon -E-mail: rakhshanda7@gmail.com
Article Type
Research Article
Date
Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026
Abstract
Clusters of transient neuropsychiatric symptoms following HPV vaccination among adolescents, particularly in school-based immunisation settings, can lead to diagnostic uncertainty, unnecessary medical interventions and public concern regarding vaccine safety. We describe a cluster of five 13-year-old schoolgirls who developed acute dizziness, brief loss of consciousness, hyperventilation and anxiety shortly after vaccination, despite normal examinations and unremarkable investigations. The clinical pattern was most consistent with vasovagal and anxiety-related reactions, although absence seizures could not be fully excluded without EEG. All recovered rapidly with reassurance, hydration and short-term symptomatic management. Awareness of such benign, self-limiting events can prevent unnecessary interventions and support vaccine confidence.
Keywords
HPV vaccine, AEFI, anxiety reaction, absence seizure, vaccine safety
Citation
Choudhary et al. Bioinformation 22(1): 518-521 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
