Title
Pathological lung tissue changes in common infectious diseases
Authors
Amit Nampalliwar1,*, Sachin Pundlikrao Ambirwar2, Swati Narayan Khandale3, Prashant Uttam Sasane4, Sheetal Suryakant Chavan5 & Chandreshwar Prasad Sinha1
Affiliation
1Department of Pathology (Roga Nidan & Vikriti Vigyana), Government Ayurved College & Hospital, Bilaspur (C.G.), Chhattisgarh, India; 2Department of Pharmacology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India; 3Department of Physiology (Kriya Sharira), Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat, India; 4Department of Internal Medicine (Kayachikitsa), All India Institute of Ayurveda, Goa, India; 5Department of Pathology (Roga Nidan & Vikriti Vigyana), Ayurved Seva Sangh's, Ayurved Mahavidyalaya, Ganeshwadi, Panchavati, Nashik, Maharashtra, India; 6Department of Internal Medicine(Kayachikitsa), Sri. N.P.A. Government Ayurved College, Raipur (C.G.), Chhattisgarh, India; *Corresponding author
Amit Nampalliwar - E-mail: dr.n.amitkumar@gmail.com; Phone: +91 9930394087
Sachin Pundlikrao Ambirwar - E-mail: ambirwarsachin@gmail.com; Phone: +91 8976298030
Swati Narayan Khandale - E-mail: drswatik@itra.edu.in; Phone: +91 9850483223
Prashant Uttam Sasane - E-mail: drprashant.sasane@aiia.gov.in; Phone: +91 8823962088
Sheetal Suryakant Chavan - E-mail: dr.sheetalyadav59@gmail.com; Phone: +91 9272642873 Chandreshwar Prasad Sinha - E-mail: drcspsinha1982@gmail.com; Phone: +91 8225000010
Article Type
Research Article
Date
Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026
Abstract
Infectious diseases of the lung remain a major cause of morbidity and mortality worldwide and their diagnosis often relies on characteristic histopathological patterns. Hence, this retrospective observational study analysed 90 archived lung biopsy, resection and autopsy specimens to compare pathological changes associated with bacterial, viral, fungal and tuberculous infections. Bacterial infections were the most common. They showed predominant acute inflammation and consolidation. Tuberculosis and fungal infections were characterized by granulomatous inflammation and caseous necrosis. Viral infections demonstrated alveolar damage. Distinct histopathological profiles correlated with specific infectious etiologies and clinical outcomes, underscoring the diagnostic and prognostic value of microscopic examination in infectious lung diseases.
Keywords
Infectious lung diseases; histopathology; pneumonia; tuberculosis; fungal infections; viral pneumonia
Citation
Nampalliwar et al. Bioinformation 22(1): 529-534 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
