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Title

Multimodal AI for pneumonia and lung cancer classification using x-ray and HRCT

 

Authors

Chauhan Pradip*, 1, Chauhan Girish2, Chauhan Bhoomika3, Vaza Jayesh4, Ratanpara Lalit1 & Mehra Simmi1

 

Affiliation

1Department of Anatomy, All India Institute of Medical Sciences, Rajkot, Gujarat, India; 2Department of Oral Pathology and Maxillofacial Surgery, Government Dental College, Jamnagar, Gujarat, India; 3Department of Obstetrics and Gynaecology, Bhagyoday Medical College, Kadi, Gujarat, India; 4Department of Orthopaedics, Narendra Modi Medical College and Hospital, Ahmedabad, Gujarat, India; *Corresponding author

 

Email

Chauhan Pradip - E-mail: prajjawalitresearch@gmail.com; Phone: +91 8866199560

Chauhan Girish - E-mail: drgirishchauhan@gmail.com

Chauhan Bhoomika - E-mail: drbhoomikachauhanchauhan@gmail.com

Vaza Jayesh - E-mail: jayesh.vaza@gmail.com

Ratanpara Lalit - E-mail:draksharphc@gmail.com

Mehra Simmi - E-mail: docsims27july@gmail.com

 

Article Type

Research Article

 

Date

Received January 1, 2026; Revised January 31, 2026; Accepted January 31, 2026, Published January 31, 2026

 

Abstract

Chest X-ray and HRCT are essential for diagnosing pneumonia and lung cancer, but their accuracy is limited. Hence, DeepScan, a multimodal AI combining CNNs trained on both imaging types, was developed using public datasets. The architecture included resnet-50 for X-rays, densenet-121 for HRCT and a late-fusion network. DeepScan outperformed single-modality models, achieving 94.6% accuracy, 95.2% sensitivity, 93.9% specificity and an AUC of 0.97 on 2,000 test patients. Multimodal integration reduced false negatives for early-stage lung cancer and improved differentiation from pneumonia, supporting earlier intervention and potentially enhancing clinical workflows.

 

Keywords

Artificial intelligence, deep learning, multimodal imaging, pneumonia, lung cancer, Chest X-Ray, HRC

 

Citation

Pradip et al. Bioinformation 22(1): 605-609 (2026)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.