Title

Comparative evaluation sealing ability: Bioceramic versus resin-based sealers by micro-CT analysis

Authors

Yelisela Rajiv Kumar¹, Aboobacker Sidheeque^2,*, Siddharth Anand³, Bharath Kandanattu⁴, Deepika Khandelwal⁵ & Gauri Singh⁶

Affiliation

¹Department of Conservative Dentistry and Endodontics, Government general hospital, DEIC, RBSK, Eluru, India; ²Department of Conservative Dentistry and Endodontics, Yenepoya Dental college, Yenepoya university, Mangalore, Karnataka, India; ³Department of Dentistry, Katihar Medical College and Hospital, Karim Bagh, Sirsa, Katihar, Bihar, India; ⁴Department of Pediatric & Preventive Dentistry, Institute of Dental Studies & Technologies, Kadrabad, Modinagar, Uttar Pradesh, India; ⁵Department of Conservative Dentistry and Endodontics, Geetanjali Dental and Research Institute, Geetanjali University, Udaipur, India; ⁶Department of Prosthodontics and Crown & Bridge, Babu Banarsi Das College of Dental Sciences, Lucknow, India; *Corresponding author

Email

Yelisela Rajiv kumar - E-mail: yrajivsmart@gmail.com; Phone: +91 9491753153
Aboobacker Sidheeque - E-mail: draboos@yahoo.com; Phone: +91 9497187857
Siddharth Anand - E-mail: drsiddharthanand@yahoo.co.in; Phone: +91 8409171918
Bharath Kandanattu - E-mail: doctorbharath99@gmail.com; Phone: +91 8722548770
Deepika Khandelwal - E-mail: khandelwaldeepika693@gmail.com; Phone: +91 9413473970
Gauri Singh - E-mail: dr.gauri781@gmail.com; Phone: +91 9532002777

Article Type

Research Article

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

Abstract

Achieving a hermetic three-dimensional seal of the root canal system remains a primary objective of endodontic therapy, yet comparative evidence on the sealing efficacy of contemporary bioceramic and resin-based sealers remains limited. Therefore, it is interest to compare the sealing ability of three bioceramic sealers (Bio-C Sealer, CeraSeal and EndoSequence BC Sealer HiFlow) with two resin-based sealers (AH Plus and ThermaSeal Plus) using micro-computed tomography. Seventy-five extracted single-rooted human premolars were obturated using single-cone technique for bioceramic sealers and warm vertical compaction for resin-based sealers, followed by three-dimensional assessment of void volume and sealer adaptation. Bioceramic sealers demonstrated significantly lower total void percentages (0.89–1.24%) compared with resin-based sealers (1.78–2.15%) (p < 0.001), with EndoSequence BC Sealer HiFlow showing the best adaptation and lowest void volume. Thus, we show that contemporary bioceramic sealers provide superior sealing ability and canal wall adaptation compared with resin-based sealers, supporting their clinical use for predictable root canal obturation.

Keywords

Bioceramic sealer, resin-based sealer, micro-CT, sealing ability, root canal obturation.

Citation

Kumar et al. Bioinformation 22(2): 702-708 (2026)

Edited by

Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.