Title
Retrospective cohort study of type 2 diabetes effects on chronic wound healing in dermatology clinics
Authors
M.R. Madan Karthik Raj1, Sailesh I.S Kumar2, Shanmukha Koppolu3 & Vijo Wilson4,*
Affiliation
1Department of General Surgery, Vinayaka Mission's Kirupanandha Variyar Medical College and Hospital, Salem, Tamil Nadu, India; 2Department of General Medicine, Madras Medical College, Tamil Nadu, India; 3Department of Trauma and Orthopaedics, Barts NHS Trust, London, England, United Kingdom; 4Department of General Medicine, Wexham Park Hospital, Frimley NHS Trust, Foundation Trust, Berkshire, United Kingdom; *Corresponding author
M.R. Madan Karthik Raj - E-mail: drmkraja@gmail.com; Phone: +91 9894333979
Sailesh I.S Kumar - E-mail: Sailesh.isk@gmail.com; Phone: +91 9486813072
Shanmukha Koppolu - E-mail: kshanmukha3@gmail.com; Phone: +447448304208
Vijo Wilson - E-mail: drvijowilson@gmail.com; Phone: +91 8668049813
Article Type
Research Article
Date
Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026
Abstract
Chronic Wounds are one of the most prevalent types of Dermatoses, which are the result of impaired Healing and Complications. In addition, Type 2 Diabetes Mellitus is one of the main causes of impaired Healing (due to the development of Complications and other factors). Therefore, it is of interest to evaluate the way T2DM influences Healing, Recurrence and Clinical Outcomes (in Dermatology Clinics) over a period of five years. A retrospective review of medical records (of chronic wound patients) identified differences between the T2DM and the Non-Diabetic Groups. The T2DM patients demonstrated a significantly longer median Healing Time than the Non-Diabetic Patients, with increased Infection Rates and an increased need for Advanced Wound Care. The rate of Recurrence and Amputation were also higher than in the Non-Diabetic Group. A Multivariate Analysis indicated that T2DM, Baseline Wound Infection and Wound Size >10 cm² were significant predictors of Delayed Healing for T2DM Patients. Thus, these data demonstrate that T2DM places a significant burden on Wound Outcomes in a Dermatology Practice. Early identification of risk factors, multidisciplinary management and optimised glycaemic control are crucial to improving Healing and reducing complications associated with Chronic Wounds and T2DM.
Keywords
Type 2 diabetes mellitus, chronic wound healing, dermatology clinics, retrospective cohort, wound infection, glycemic control, multidisciplinary care
Citation
Raj et al. Bioinformation 22(2): 853-858 (2026)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
