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Title

Xenografts and platelet-rich fibrin impact on maxillary sinus augmentation: A comparative clinical histomorphometric study

 

Authors

Abhishek Motimath1, S. Sonal2, C.D. Mouneshkumar3,*, Vinod Kumar Kirar4, Braina P. Jadav5, Hetul Patel6 & Santosh Kumar7

 

Affiliation

1Department of Oral and Maxillofacial Surgery, KLE V K Institute of Dental Sciences, Karnataka, India; 2Department of Dental Surgery, ESIC Medical College & Hospital, Noida, India; 3Department of Oral and Maxillofacial Surgery, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Satara, Maharashtra, India; 4Department of Periodontology, Jaipur Dental college MVG University, Dhand, Jaipur, India; 5Department of Dentistry, Gujarat Medical Education and Research Society, Morbi, Gujarat, India; 6Department of Oral Medicine & Radiology, Faculty of Dental Science, Dharmsinh Desai University, Nadiad,Gujarat, India; 7Department of Periodontology & Implantology, Karnavati University, Uvarsad, Gandhinagar, Ahmedabad, Gujarat, India; *Corresponding author

 

Email

Abhishek Motimath - E-mail: abhi_motimath@yahoo.com
S. Sonal - E-mail: drsonal.delhi@gmail.com
C.D. Mouneshkumar - E-mail: drmouneshkumarchapi07@gmail.com
Vinod Kumar Kirar - E-mail: drvinod.dentalsurgeon@gmail.com
Braina P. Jadav - E-mail: doc.brainsradiologist22@gmail.com
Hetul Patel - E-mail: hetulpatel.fods@ddu.ac.in
Santosh Kumar - E-mail: santoshkumar@karnavatiuniversity.edu.in

 

Article Type

Research Article

 

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

 

Abstract

Insufficient posterior maxillary bone height limits implant placement in atrophic ridges. Therefore, it is of interest to compare deproteinized bovine bone mineral (DBBM) versus DBBM with advanced platelet-rich fibrin (A-PRF) in 60 sinuses across 30 patients undergoing lateral window sinus augmentation. Histomorphometry showed greater new bone formation [42.8 (6.4%) vs. 31.2 (5.9%), p=0.001) and less residual graft [28.4 (4.7) vs. 41.6 (6.1%), p=0.001] in the A-PRF group. Test sites also demonstrated improved bone density, graft height stability and 100% implant survival at 9 months. A-PRF accelerates bone regeneration and reduces graft resorption in sinus augmentation, advancing biologic augmentation strategies.

 

Keywords

Maxillary sinus augmentation; xenografts; platelet-rich fibrin; deproteinized bovine bone mineral; histomorphometry; bone regeneration; implant survival

 

Citation

Motimath et al. Bioinformation 22(2): 912-916 (2026)

 

Edited by

Vini Mehta

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.