Title

Cardiovascular risk factors in fasting and postprandial lipid profiles among type 2 diabetes patients

Authors

Sukh Dayal Kumhar¹, Praveen Kumar Tagore¹, Jitendra Kanjolia¹, Ashis Tiwari^1,*, Abha Bardiya² & Shivani Parihar³

Affiliation

¹Department of General Medicine, Government Medical College, Datia, Madhya Pradesh, India; ²Department of Anaesthesiology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India; ³Department of Pathology, Chirayu Medical College, Bhopal, Madhya Pradesh, India; *Corresponding author

Email

Sukh Dayal Kumhar - E-mail: dr.sd.prajapati@gmail.com
Praveen Kumar Tagore - E-mail: tagore.praveen@gmail.com
Jitendra Kanjolia - E-mail: jitendrakanjolia@gmail.com
Ashis Tiwari - E-mail: ashishtiwari.gwldr@gmail.com
Abha Bardiya - E-mail: bardiya.abha@gmail.com
Shivani Parihar - E-mail: drshivaniparihar199@gmail.com

Article Type

Research Article

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

Abstract

Cardiovascular disease (CVD) dominates Type 2 Diabetes Mellitus (T2DM) mortality, yet fasting lipid profiles may miss atherogenic postprandial lipemia effects. Therefore, it is of interest to compare fasting versus postprandial lipids (4h post-high-fat meal) in 240 T2DM patients against Carotid Intima-Media Thickness (CIMT) as atherosclerosis surrogate. Fasting Low-Density lipoprotein (LDL) showed moderate CIMT correlation (r=0.68, p=0.001), but postprandial triglycerides/remnant cholesterol demonstrated stronger associations and independent multivariate prediction. Fasting triglycerides lacked significance. Postprandial lipids advance T2DM CVD risk assessment beyond fasting measures, supporting non-fasting protocols for better stratification.

Keywords

Type 2 diabetes mellitus, postprandial lipemia, cardiovascular risk, carotid intima-media thickness, and triglycerides.

Citation

Kumhar et al. Bioinformation 22(2): 922-926 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.