Title

Bispectral index-guided versus standard anaesthesia monitoring for intraoperative awareness prevention

Authors

Brajesh Kumar¹, Nancy Ekka², Aditya Singh Chauhan² & Sourabh Shrivastava^2,*

Affiliation

¹Consultant Anaesthesiologist, Bansal Hospital, Sagar, Madhya Pradesh, India; ²Department of Anaesthesiology, Gajra Raja Medical college Gwalior, Madhya Pradesh, India; *Corresponding author

Email

Brajesh Kumar - E-mail: brajeshparihar1@gmail.com
Nancy Ekka - E-mail: drnancyekka21@gmail.com

Aditya Singh Chauhan - E-mail: adityaschauhan88@gmail.com
Sourabh Shrivastava -E-mail: sourabhjitu@gmail.com

Article Type

Research Article

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

Abstract

Although bispectral index (BIS) monitoring provides an objective measure of hypnotic depth, its routine use to prevent awareness remains debated due to conflicting evidence and cost considerations. Therefore, it is of interest to evaluate BIS-guided versus clinically guided sevoflurane anaesthesia in 200 adults undergoing elective surgery over 60 minutes. No definite intraoperative awareness occurred in either group, confirmed by modified Brice interviews up to 30 days postoperatively. BIS monitoring reduced sevoflurane consumption by 24% (1.7 ± 0.4 vs 2.2 ± 0.5 MAC-hours; p < 0.001) and accelerated extubation (7.9 ± 2.3 vs 10.8 ± 3.1 min; p < 0.001) and PACU discharge (46.2 ± 11.8 vs 56.9 ± 14.7 min; p < 0.001). It also provided greater haemodynamic stability, with lower MAP variability (11.4 ± 3.9% vs 16.8 ± 5.6%; p < 0.001). BIS monitoring optimizes anaesthetic delivery and recovery efficiency without lowering awareness incidence compared to vigilant clinical monitoring.

Keywords

Bispectral index (BIS), intraoperative awareness, depth of anaesthesia monitoring, sevoflurane consumption, recovery profile, haemodynamic stability, explicit recall

Citation

Kumar et al. Bioinformation 22(2): 931-934 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.