Title

Efficacy of arthrocentesis and PRP in TMJ osteoarthritis patients

Authors

Cheena Singh¹, Ashish Kalawat^2,*, Kiran Kumari³, Abhigyan Manas⁴, Madhuri S Sale⁵, Pushkar Gupta⁶, Rajat Misurya⁷

Affiliation

¹Department of Oral Medicine and Radiology, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India; ²Department of Orthodontics and Dentofacial Orthopaedics, Maharaja Ganga Singh Dental College and Research Centre, Sri Ganganagar, Rajasthan, India; ³Department of Dentistry, Autonomous State Medical College, Firozabad, Uttar Pradesh, India; ⁴Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh , India; ⁵Department of Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India; ⁶Department of Prosthodontics and Crown & Bridge, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh, India; ⁷Department of Dentistry, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India*Corresponding author

Email

Cheena Singh - E-mail: cheenasngh3@gmail.com; Phone: +91 9864378674

Ashish Kalawat - E-mail: drashishkalawat@gmail.com; Phone: +91 9444377533

Kiran Kumari - E-mail: k.kumari1612@gmail.com; Phone: +91 9884379772

Abhigyan Manas - E-mail: abhigyanmanas@gmail.com; Phone: +91 993653993

Madhuri S Sale - E-mail: drmadhurisp@gmail.com; Phone: +91 9884378341

Pushkar Gupta - E-mail: drpushkar1@gmail.com; Phone: +91 9884376564

Rajat Misurya - E-mail: rajatmisurya1@rediffmail.com; Phone: +91 9874376785

Article Type

Research Article

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

Abstract

Arthrocentesis has emerged as a well-established minimally invasive procedure for temporomandibular joint osteoarthritis (TMJ-OA). Conservative therapies often provide limited and short-term symptomatic relief. Therefore it is of interest to assess the clinical efficacy of arthrocentesis combined with platelet-rich plasma (PRP) injection in reducing pain and recovering mandibular function in patients with TMJ osteoarthritis. Hence, total 38 patients diagnosed with TMJ-OA underwent arthrocentesis followed by intra-articular injection of autologous PRP. Clinical outcomes assessed included pain intensity using the Visual Analog Scale (VAS) and maximum mouth opening at 1, 3 and 6 months. Arthrocentesis combined with PRP provides sustained pain relief and functional improvement in TMJ-OA.

Keywords

Arthrocentesis, mandibular function, minimally invasive therapy, platelet-rich plasma (PRP), pain management, temporomandibular joint osteoarthritis

Citation

Singh et al. Bioinformation 22(2): 1004-1008 (2026)

Edited by

P Babaji

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.