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Title

Predictors of mortality and rebleeding in acute upper gastrointestinal bleeding: A prospective hospital-based study

 

Authors

Shrey Singh, Mohamad Akram* & Saurabh Singh

 

Affiliation

Department of Medicine, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Jolly Grant, Dehradun, India; *Corresponding author

 

Email

Shrey Singh - E-mail: sshrey151@gmail.com
Mohamad Akram - E-mail: drmohamad.akram@outlook.com

Saurabh Singh - E-mail: drsingh.saurabh@gmail.com

 

Article Type

Research Article

 

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

 

Abstract

Acute upper gastrointestinal bleeding is a major emergency cause of transfusion and in hospital death but local data on mortality and rebleeding predictors is limited. This prospective observational study included 138 adults, most were males 66.7% and age 31–50 years 40.6% with frequent alcohol use 43.5% and NSAID exposure 36.2%. Peptic ulcer disease was the commonest cause 56.5% followed by variceal bleed 25.4% and severe anaemia Hb <7 g/dL was present in 29% with transfusion required in 63.8%. Endoscopic hemostasis was achieved in 87% but rebleeding occurred in 13% and mortality was 9.4% with variceal bleed contributing most rebleeds and peptic ulcer disease accounting for most deaths, so early risk scoring fast endoscopy and correction of reversible host factors remains important.

 

Keywords

Gastrointestinal hemorrhage, peptic ulcer hemorrhage, esophageal varices, risk factors, hospital mortality, rebleeding.

 

Citation

Singh et al. Bioinformation 22(2): 1109-1112 (2026)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.