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Title

Anti-biofilm efficacy of nano calcium hydroxide and chitosan nanoparticles against E. faecalis

 

Authors

Aakriti Bansal, Ashwini Gaikwad*, Aniket Jadhav, Ruchira Bhamare & Rajlaxmi Patil

 

Affiliation

Department of Conservative Dentistry and Endodontics, Bharati Vidyapeeth Deemed to be University Dental College and Hospital, Pune, India; *Corresponding author

 

Email

Aakriti Bansal - E-mail: aakriti.bansal15@gmail.com
Ashwini Gaikwad - E-mail: ashwini.gaikwad@bharatividyapeeth.edu
Aniket Jadhav - E-mail: aniket.jadhav@bharatividyapeeth.edu

Ruchira Bhamare - E-mail: ruchira.bhamare@bharatividyapeeth.edu
Rajlaxmi Patil - E-mail: rajlaxmi.patil@bharatividyapeeth.edu

 

Article Type

Research Article

 

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

 

Abstract

Enterococcus faecalis is among the microorganisms frequently isolated from root canal infections. The outcome of the endodontic treatment depends on the effective disinfection of the root canal system. Therefore, it is of interest to assess the potential of Nano Calcium Hydroxide and Chitosan Nanoparticles as intracanal medicaments against Enterococcus faecalis biofilm. Hence, a total of twenty-eight single-rooted dental elements were included, where the incisal end of individual elements was infected with Enterococcus faecalis. The two medicaments used as intracanal dressing materials were Nano Calcium Hydroxide and Chitosan Nanoparticles. Enterococcus faecalis bacteria exposed to Nano Calcium Hydroxide was significantly higher as compared to those exposed to Chitosan Nanoparticles.

 

Keywords

Antibacterial efficacy, biofilm, chitosan nanoparticles, enterococcus faecalis, intracanal medicament, nano calcium hydroxide root canal disinfection

 

Citation

Bansal et al. Bioinformation 22(2): 1126-1130 (2026)

 

Edited by

P Babaji

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.