Title

Effectiveness of tetracycline fibers as an adjunct to scaling and root planing in chronic periodontitis

Authors

Mohammad Arifkhan¹, Neetu Rani², Shailja Singh³, Mohd Ayub Siddiqui⁴, Sachin Kumar^5,*, Mohsin Khan⁶ & Ganiga Channaiah Shivakumar⁷

Affiliation

¹Department of Periodontology, Career Post Graduate Institute of Dental Science, Lucknow, Uttar Pradesh, India; ²Department of Periodontology, Faculty of Dental Sciences, KGMU, Lucknow, Uttar Pradesh, India; ³Department of Conservative Dentistry and Endodontics, KGMU, Lucknow, Uttar Pradesh, India; ⁴Department of Oral and Maxillofacial Surgery, Career Post Graduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India; ⁵Department of Oral and Maxillofacial Surgery, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India; ⁶Department of Oral and Maxillofacial Surgery, Career Post Graduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India; ⁷Department of Oral Medicine & Radiology, People's College of Dental Sciences and Research Centre, People's University, Bhopal, India; *Corresponding author

Email

Mohammad Arifkhan - E-mail: makperio013@gmail.com
Neetu Rani - E-mail: neeturani0283@gmail.com
Shailja Singh - E-mail: shailja.singh@kgmcindia.edu
Mohd Ayub Siddiqui - E-mail: ayyub1siddiqui@gmail.com
Sachin Kumar - E-mail: sachin.kumar1@Sharda.ac.in
Mohsin Khan - E-mail: docmohsinkhan786@gmail.com
Ganiga Channaiah Shivakumar - E-mail: shiva21375@gmail.com

Article Type

Research Article

Date

Received February 1, 2026; Revised February 28, 2026; Accepted February 28, 2026, Published February 28, 2026

Abstract

Chronic periodontitis remains highly prevalent and scaling and root planing alone may be insufficient to achieve optimal clinical improvement at moderate periodontal pocket depths. Therefore, it is of interest to clinical efficacy of scaling and root planing alone with scaling and root planing combined with tetracycline-impregnated collagen fibers in patients with chronic periodontitis. Thirty patients (60 sites) with probing depths of 4–7 mm were treated using a split-mouth design and plaque index, gingival index, probing depth and clinical attachment level were recorded at baseline and follow-up. Both groups showed significant improvement in clinical parameters, with the test group demonstrating greater probing depth reduction and clinical attachment gain at 90 days compared to controls. Adjunctive use of tetracycline-impregnated collagen fibers enhanced the clinical outcomes of scaling and root planing in the short-term management of chronic periodontitis.

Keywords

Tetracycline, local drug delivery system, chronic periodontitis, scaling and root planing, clinical study

Citation

Arifkhan et al. Bioinformation 22(2): 1137-1143 (2026)

Edited by

Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.