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Title

Linking vitamin D levels with recurrent wheeze among Indian children

 

Authors

Emmadi Vineeth Reddy, Chaparala Sarishma* & Bonela Sai Kumar

 

Affiliation

Department of Paediatrics, GITAM Institute of Medical Sciences and Research, GITAM Deemed to be University, Rushikonda, Visakhapatnam, Andhra Pradesh, India; *Corresponding author

 

Email

Emmadi Vineeth Reddy - E-mail: vemmadi@gitam.in
Chaparala Sarishma - E-mail: schapara@gitam.edu
Bonela Sai Kumar - E-mail: sbonela@gitam.edu

 

Article Type

Research Article

 

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

 

Abstract

Vitamin D deficiency (<20 ng/mL) in children aged 1-5 is linked to higher recurrent wheeze risk via immune dysregulation, but supplementation trials show mixed results. Therefore, it is of interest to assess the association between vitamin D deficiency in children and recurrent wheeze in children aged 1 to 5 years. The total sample size was 80 and the data regarding the patient demographic variables, history of symptoms and allergy, GERD-related recurrent aspiration, history of nebulization, hospital stay etc. were collected using standard Questionnaire. The mean vitamin D level in the study participants was 27.18 ± 7.86 ng/mL and out of 80 cases, the majority, 45% of patients, had WALRI, followed by 27.5% of patients who had pneumonia. Among patients with five wheeze episodes per year, maximum patients 71.4% showed vitamin D levels 11 to 30ng/ml. Thus, Vitamin D supplementation programmes on a national scale help reduce the epidemic of vitamin D insufficiency.

 

Keywords

Vitamin D, atopy, WALRI, rhinitis, wheeze

 

Citation

Reddy et al. Bioinformation 22(3): 1289-1294 (2026)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.