Single-visit versus two-visit endodontic treatment for postoperative pain in asymptomatic non-vital mandibular premolars

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Title	Single-visit versus two-visit endodontic treatment for postoperative pain in asymptomatic non-vital mandibular premolars
Authors	Pooja Bala¹, Poonam Bogra¹, Swati Chhabra^2,*, Nikita Goyal¹, Niharika Soni¹, Himani Arora¹ & Surinder Sachdeva³
Affiliation	¹Department of Conservative Dentistry and Endodontics, J.N. Kapoor DAV Centenary Dental College, Yamunanagar, Haryana, India; ²Department of Conservative Dentistry and Endodontics, M.M College of Dental Sciences and Research, MM (Deemed to be University), Mullana, Ambala, India; ³Department of Periodontics, M.M College of Dental Sciences and Research, Maharishi Markandeshwar (Deemed to be University), Mullana (Ambala), Haryana, India; *Corresponding author
Email	Niharika Soni - E-mail: Niharika.Soni725@gmail.com Poonam Bogra - E-mail: Poonambogra@yahoo.In Swati Chhabra - E-mail: Endoswatichhabra@gmail.com; Phone: +91 9034743780 Nikita Goyal - E-mail: Nktagyl1995@gmail.com Himani Arora - E-mail: Ahimani35@gmail.com Pooja Bala - E-mail: Pbdentalcare@gmail.com Surinder Sachdeva - E-mail: sksperio@gmail.com
Article Type	Research Article
Date	Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract	Postoperative pain is one of the primary problems in endodontic treatment and the ideal protocol for managing non-vital teeth through single-visit or multiple-visit endodontic treatment remains unsettled. Therefore, it is of interest to compare postoperative pain following single-visit endodontic therapy using 5% Iodine Potassium Iodide (IKI) as a final irrigant with that is following two-visit treatment using calcium hydroxide as an intracanal medicament. Seventy asymptomatic non-vital mandibular premolars were randomly assigned to two groups. Postoperative pain was assessed using Visual Analog Scale at 24, 48, 72 hours, and one week after obturation. Both groups showed a similar trend of pain reduction over time. The mean pain scores were slightly lower in the IKI group at all intervals, though the differences were not statistically significant.
Keywords	Calcium hydroxide, intracanal medicament, iodine potassium iodide (IKI), postoperative pain, single-visit root canal, two-visit root canal.
Citation	Bala et al. Bioinformation 22(3): 1302-1305 (2026)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.