Title
Intravenous versus inhalational maintenance anaesthesia on postoperative recovery parameters after general anaesthesia: A randomized controlled study
Authors
Leena Rohilla1,*, Ritu Sharma2 & Rajeev Lochan Tiwari2
Affiliation
1Department of Anaesthesia, Maharishi Chyawan Medical College, Koriawas Narnaul, Haryana, India; 2Department of Anaesthesia, Fortis Escorts Hospital, Jaipur, Rajasthan, India; *Corresponding author
Leena Rohilla - E-mail: leena.rohilla003@gmail.com; Phone: +91
8168360758
Ritu Sharma - E-mail: jaipurdrhimanshu@yahoo.com; Phone: +91
9829144467
Rajeev Lochan Tiwari - E-mail: rajeev.tiwari@fortishealthcare.com;
Phone: +91 9414042352
Article Type
Research Article
Date
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract
Total intravenous anaesthesia (TIVA) using propofol-remifentanil versus sevoflurane maintenance affects postoperative recovery, PONV and patient outcomes in laparoscopic surgery, though evidence varies. Hence, this randomised trial compared TIVA (n=60) versus sevoflurane (n=60) in 120 ASA I-III adults undergoing elective laparoscopic cholecystectomy with standardised protocols. TIVA accelerated extubation (7.4±2.1 vs 9.6±2.5 min; p<0.001), Aldrete ≥9 recovery (23.1±4.8 vs 29.2±6.1 min; p<0.001) and shortened PACU stay (40 [35-45] vs 50 [42-60] min; p=0.002). TIVA reduced PONV incidence (20% vs 38.3%; p=0.03) with less rescue antiemetic use, while pain scores and opioid requirements stayed comparable between groups. Propofol-remifentanil TIVA optimises early recovery, lowers PONV and boosts 24-hour QoR-15 scores versus sevoflurane, positioning it as the superior choice for enhanced postoperative outcomes.
Keywords
Total intravenous anaesthesia (TIVA); inhalational anaesthesia; propofol; sevoflurane; postoperative recovery; QoR-15; postoperative nausea and vomiting (PONV)
Citation
Rohilla et al. Bioinformation 22(3): 1361-1366 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
