Title
Authors
Affiliation
1Department of Microbiology, AIIMS, Bhopal, Madhya Pradesh, India; 2Department of Microbiology, MGM Medical College, Indore, Madhya Pradesh, India; 3Department of Microbiology, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh, India; *Corresponding author
Apoorva Devgade - E-mail: apoorva2015@gmail.com; Phone: +91
8871200979
Nishat Khan - E-mail: drnishatgorie@yahoo.com; Phone: +91 9993588778
Anita Mutha - E-mail: dranitamutha@gmail.com; Phone: +91 9826170789
Article Type
Research Article
Date
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract
Hepatitis B virus (HBV) infection during pregnancy significantly risks mother-to-child transmission, particularly among HBeAg-positive mothers requiring routine antenatal screening. This hospital-based cross-sectional study assessed HBsAg and HBeAg seroprevalence among pregnant women attending an antenatal clinic from January to December 2023. Serum samples underwent ELISA testing for HBsAg, with HBeAg evaluation for all positive cases, revealing overall HBsAg seroprevalence of 2.0%. Among HBsAg-positive women, 33.3% demonstrated HBeAg positivity, identifying high-risk cases for perinatal transmission. These findings advance maternal health protocols by confirming the necessity of targeted antenatal screening and preventive strategies to minimize HBV vertical transmission.
Keywords
Hepatitis B virus (HBV); seroprevalence; hepatitis B e antigen (HBeAg); pregnant women; antenatal screening
Citation
Devgade et al. Bioinformation 22(3): 1421-1424 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
