Title

Herpetic viral dominance in pediatric meningitis and meningoencephalitis

Authors

Pooja Mishra¹, Shweta Chauhan Pandey¹, Surjeet Kumar Shukla², Anusha Sharma³, Shubham Prakash Singh⁴, Manoj B Jais⁴, Soumya Tiwari⁵, Sanjib Gogoi⁴ & Vikash Yadav^4,*

Affiliation

¹Department of Microbiology, Sunderlal Patwa Government Medical College (SPGMC), Mandsaur, Madhya Pradesh, India; ²Department of Pediatrics, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India; ³Department of Microbiology, Dr Babasaheb Ambedkar Hospital, New Delhi, India; ⁴Department of Microbiology, Lady Hardinge Medical College (LHMC), New Delhi, India; 5Department of Pediatrics, LHMC and Associated Hospitals, New Delhi, India; *Corresponding author

Email

Pooja Mishra - E-mail: mishraashaily9@gmail.com
Shweta Chauhan Pandey - E-mail: drshweta.pandey11@gmail.com
Surjeet Kumar Shukla - E-mail: shuklasurjeet@gmail.com
Anusha Sharma - E-mail: anusha00s4@gmail.com
Shubham Prakash Singh - E-mail: theshubhamprakash07@gmail.com
Manoj B Jais - E-mail: drmanojjais@yahoo.co.in
Soumya Tiwari - E-mail: soumyaakshay@gmail.com
Sanjib Gogoi - E-mail: drgogoisanjib24@gmail.com
Vikash Yada - E-mail: Vikuvns.bhuav@gmail.com

Article Type

Research Article

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

Abstract

Viral meningitis, caused by various viruses including Enteroviruses, Herpes simplex viruses and others, poses challenges in diagnosis due to its overlapping symptoms with other conditions. Therefore, it is of interest to evaluate the efficacy of RTPCR in detecting viral causes of meningitis in pediatric patients with suspected viral infections. Hence, a total of 62 CSF samples were analyzed, revealing a high prevalence of HSV2 and Parvovirus B19 among others. The study found RTPCR to be a sensitive and rapid method for identifying viral pathogens. This research advances knowledge by demonstrating RTPCR's utility in quickly identifying viral causes, aiding in timely and targeted treatment.

Keywords

Viral meningitis, aseptic meningitis, herpetic meningitis, molecular detection meningitis, pediatric viral meningitis

Citation

Mishra et al. Bioinformation 22(3): 1448-1452 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.