Title

CRP and IL-6 as cardiovascular risk markers in diabetes

Authors

Najmush Sahar Khan^1,*, Ravi Ramkishan Yadav², Shweta Kumari³, Parth Jani⁴, Jeremy Mathias Calderón Torres⁵ & Chennakesavulu Dara⁶

Affiliation

¹Department of Physiology, Santosh Deemed to be University, Ghaziabad, Delhi NCR, India; ²Department of Biochemistry, TS Misra Medical College and Hospital, Amousi, Lucknow, Uttar Pradesh, India; ³Department of Biotechnology, Savitribai Phule Pune University, Pune, Maharashtra, India; ⁴Department of General Medicine, Government Medical College, Bhavnagar, Gujarat, India; ⁵Department of Medicine, Pontifical Catholic University of Ecuador, Quito, Ecuador; 6Department of General Medicine, ESIC Medical College, Hyderabad, India; *Corresponding author

Email

Najmush Sahar Khan - E-mail: drnajmushz@yahoo.com
Ravi Ramkishan Yadav - E-mail: drraviaugust@gmail.com
Shweta Kumari - E-mail: shwetavaanya@gmail.com
Parth Jani - E-mail: parthjani13@gmail.com
Jeremy Mathias Calderón Torres - E-mail: jeremyct365@gmail.com
Chennakesavulu Dara - E-mail: augnus2k3@gmail.com

Article Type

Research Article

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

Abstract

Cardiovascular diseases (CVD) are a leading cause of mortality in patients with diabetes mellitus and identifying biomarkers that predict cardiovascular risk is critical for early intervention. Therefore, it is of interest to explore the role of inflammatory markers, specifically CRP and IL-6, in predicting cardiovascular risk among diabetic patients. Elevated levels of both markers were found to be significantly associated with higher cardiovascular risk, as assessed by the Framingham Risk Score. Data show that CRP and IL-6 can serve as valuable biomarkers for identifying diabetic individuals at increased cardiovascular risk. This study advances knowledge by demonstrating that inflammation, as reflected by CRP and IL-6 levels, is an important predictor of cardiovascular events in diabetic patients.

Keywords

C-reactive protein (CRP), diabetes, interleukin-6 (IL-6), inflammation, cardiovascular risk

Citation

Khan et al. Bioinformation 22(3): 1453-1456 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.