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Title |
FibroScan grading and metabolic correlates of fatty liver disease
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Authors |
Hemant Kumar Jain1,*, Jitendra Kanjolia1, Aparna Mittal1 & Shivani Parihar2
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Affiliation |
1Department of General Medicine, Government Medical College, Datia, Madhya Pradesh, India; 2Department of Pathology, Chirayu Medical College, Bhopal, Madhya Pradesh, India; *Corresponding author
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Hemant Kumar Jain - E-mail: hk5256@yahoo.co.in
Aparna Mittal - E-mail: aparnamittal.mittal@gmail.com
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Article Type |
Research Article
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Date |
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
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Abstract |
Fatty liver disease is increasingly recognized as a hepatic manifestation of systemic metabolic dysfunction. This cross-sectional study, conducted among 165 adult patients with ultrasonographic evidence of fatty liver disease, evaluated metabolic risk factors and liver involvement using FibroScan for steatosis grading and liver stiffness measurement. The results revealed a high prevalence of metabolic syndrome, insulin resistance, dysglycemia and atherogenic dyslipidemia among participants, with moderate to severe hepatic steatosis being common. FibroScan grades showed a significant association between higher steatosis levels and worsening metabolic profiles, including body composition, glycemic parameters and insulin resistance. Thus, we show FibroScan as a valuable non-invasive tool for identifying patients at increased metabolic and hepatic risk, allowing for early risk stratification and management. |
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Keywords |
Fatty liver disease; FibroScan; controlled attenuation parameter; metabolic syndrome; insulin resistance; liver fibrosis
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Citation |
Jain et al. Bioinformation 22(3): 1487-1490 (2026)
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Edited by |
P Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
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