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Title

AI based prediction of chemotherapy response in cancer patients: A cross-sectional study

 

Authors

Vipin Kharade1,*, Tapesh Pounikar2 & Chetna Devkar3

 

Affiliation

1Department of Radiation Oncology, All India Institute of Medical Sciences Bhopal, Madhya Pradesh, India; 2Department of Radiation Oncology, Chhindwara Institute of Medical Sciences, Chinaware, Madhya Pradesh, India; 3Department of Computer Sciences & Engineering, National Institute of Technology, Bhopal, Madhya Pradesh, India; *Corresponding author

 

Email

Vipin Kharade - E-mail: vipin.radiotherapy@aiimsbhopal.edu.in
Tapesh Pounikar - E-mail: tapeshpounikar@gmail.com
Chetna Devkar - E-mail: rgtu.chetna@gmail.com

 

Article Type

Research Article

 

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

 

Abstract

Predicting chemotherapy response remains challenging due to the variability in tumor biology, genetics and host factors. Therefore, it is of interest to evaluate the effectiveness of AI-based predictive models in assessing chemotherapy response in cancer patients. AI models demonstrated high accuracy in distinguishing responders from non-responders, with those integrating multiple data types outperforming single-domain models. The integration of clinical, radiological and laboratory data significantly enhanced prediction accuracy. Therefore, this study advances knowledge by highlighting the potential of AI in revolutionizing chemotherapy response prediction and contributing to more targeted, effective cancer treatments

 

Keywords

Artificial intelligence, chemotherapy response, machine learning, oncology, personalized medicine

 

Citation

Kharade et al. Bioinformation 22(3): 1515-1517 (2026)

 

Edited by

Ritik Kashwani

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.