Title

Prevalence of orthokeratinized odontogenic cyst: A retrospective clinicopathological study

Authors

Gurmej Singh Warval¹, Jasbir Kaur², Rohit Chopra³, Natasha Attri⁴, Ujjwal Chawla⁵,* & Yogita Garg⁶

Affiliation

¹Department of Oral and Maxillofacial Surgery, Government Dental College, Patiala, India; ²Department of Dentistry, Guru Gobind Singh Medical College and Hospital, Faridkot, India; ³Department of Periodontics, Guru Gobind Singh Medical College and Hospital, Faridkot, India; ⁴Department of Periodontics, Punjab Government dental college, Amritsar, India; ⁵Department of Oral and maxillofacial surgery, Dasmesh Institute of Research and Dental Science, Faridkot, India; ⁶Department of Periodontics, Government Dental College, Patiala, India; *Corresponding author

Email

Gurmej Singh Warval - E-mail: gurmejgdc85@gmail.com; Phone: +91 6283435694
Jasbir Kaur - E-mail: Jasbirchopra76@gmail.com; Phone: +91 7973140837
Rohit Chopra - E-mail: Choprarohit76@yahoo.co.in; Phone: +91 8847219897
Natasha Attri - E-mail: dr_natashaattri@yahoo.co.in; Phone: +91 88727 11121
Ujjwal Chawla - E-mail: chawla.ujjwal007@gmail.com; Phone: +918708911393
Yogita Garg - E-mail: yogita05garg@gmail.com; Phone: +91 9517585005

Article Type

Research Article

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

Abstract

Orthokeratinized odontogenic cyst is a distinct developmental jaw cyst commonly misinterpreted at the clinical and radiographic level due to overlap with other keratinizing and tooth-associated cysts. Hence, 1,200 biopsy specimens were analyzed, identifying 30 histologically confirmed OOC cases. OOC constituted 10.0% of all odontogenic cysts and 2.5% of the total biopsy cohort. The majority of lesions affected males between 21–30 years and were predominantly located in the posterior mandible, frequently involving impacted teeth, especially the mandibular third molar. The study highlights its rarity, limited tissue aggression and the importance of microscopic confirmation for accurate diagnosis and appropriate treatment planning

Keywords

Orthokeratinized odontogenic cyst (OOC), prevalence, odontogenic cysts, mandible, clinicopathological features, impacted tooth, histopathology, unilocular radiolucency, retrospective study, jaw cystic lesions.

Citation

Warval et al. Bioinformation 22(3): 1518-1521 (2026)

Edited by

Neelam Goyal & Shruti Dabi

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.