Title
Fitness parameters as a marker of cardiac autonomic neuropathy among diabetes mellitus patients
Authors
Jagrati Nagar1, S.M. Hulke1,*, G.A. Birajdar2, A.E. Thakare1, R.N. Bharshankar1, Santosh Wakode1 & Y.P. Vaidya3
Affiliation
1Department of Physiology, All India Institute of Medical Sciences, Bhopal, India; 2Department of Physiology, PMC, Parbhani, Maharashtra, India; 3Department of Anatomy, Peoples Medical College and Research Centre, Bhopal, India; *Corresponding author
Jagrati Nagar - E-mail: jagrati26012000@gmail.com
S.M Hulke - E-mail: smh555@rediffmail.com,
sandip.physiology@aiimsbhopal.edu.in
G.A. Birajdar - E-mail: drgurubirajdar@gmail.com
A.E Thakare - E-mail: avinash.physiology@aiimsbhopal.edu.in
R.N Bharshankar - E-mail: rajay.physiology@aiimsbhopal.edu.in
Santosh Wakode - E-mail: head.physiology@aiimsbhopal.edu.in
Y.P. Vaidya - E-mail: yugavaidya@rediffmail.com
Article Type
Research Article
Date
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract
The role of fitness parameters as a marker of cardiac autonomic neuropathy in the diagnosis of diabetes mellitus is of interest. Hence, a cross-sectional study was conducted at AIIMS, Bhopal, on 110 diagnosed cases of diabetes mellitus, where patients had undergone fitness assessment and autonomic function assessment using Ewing’s battery of autonomic reactivity and heart rate variability assessment. A significant difference was observed in cardiovascular endurance and abdominal strength between early to regular involvement of cardiac autonomic neuropathy and definite to severe involvement. However, no significant correlations were observed between fitness parameters, the autonomic function involvement score and heart rate variability parameters. Cardiovascular endurance may act as an early marker of cardiac autonomic neuropathy in diagnosed cases of diabetes mellitus; thus, fitness assessment may be recommended for diabetes mellitus patients. However, longitudinal studies are recommended in this regard.
Keywords
Cardiac autonomic neuropathy (CAN), diabetes mellitus, fitness assessment
Citation
Nagar et al. Bioinformation 22(3): 1564-1568 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
