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Title

Correlation of serum ferritin and D-Dimer levels with clinical outcomes among hospitalized Indian patients

 

Authors

Pankaj Kumar Jain1, Mahavir Raghunath Mundra2 & Lalan Pratap Singh3,*

 

Affiliation

1Department of General Medicine, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India; 2Department of Biochemistry, N.K.P. Salve Institute of Medical Sciences & Research Centre and Lata Mangeshkar hospital, Nagpur, Maharashtra, India; 3Department of General Medicine, Government Medical College, Satna, Madhya Pradesh, India; *Corresponding author

 

Email

Pankaj Kumar Jain - E-mail: drpankajjain07@gmail.com; Phone: +91 9827785717
Mahavir Raghunath Mundra - E-mail: drmahavir123@yahoo.in; Phone: +91 8261875172
Lalan Pratap Singh - E-mail: lalanmgm1986@gmail.com; Phone: +91 700021816

 

Article Type

Research Article

 

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

 

Abstract

Serum ferritin and D-dimer are established biomarkers reflecting inflammatory activity and coagulation disturbances, both of which are linked to adverse outcomes in hospitalized individuals. Therefore, it is of interest to determine the relationship between admission ferritin and D-dimer levels and unfavorable clinical outcomes in hospitalized adults. In this cross-sectional observational analysis of 200 patients, biomarker levels obtained within 24 hours of admission were evaluated in relation to intensive care requirement and in hospital mortality using correlation analysis, multivariable logistic regression and receiver operating characteristic curve analysis. Thus, serum ferritin and D-dimer levels, when assessed together at admission, provide valuable predictive insight into adverse clinical outcomes, offering potential for early prognostic evaluation and improved risk stratification in hospitalized patients.

 

Keywords

serum ferritin, D-dimer, risk stratification, intensive care, mortality prediction, biomarkers

 

Citation

Jain et al. Bioinformation 22(3): 1643-1646 (2026)

 

Edited by

Ritik Kashwani

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.