Title
Evaluation of aloe extracts as a photosensitizer in antimicrobial photodynamic therapy against Porphyromonas gingivalis: An in vitro study
Authors
Allen Naorem*, Vishakha Patil, Vidya Dodwad & Priyanka Zerwal
Affiliation
Department of Periodontology, Bharati Vidyapeeth (deemed to be university) Dental College and Hospital, Pune, Maharashtra, India; *Corresponding author
Allen Naorem - E-mail: allen.naorem@gmail.com
Vishakha Patil - E-mail: vishakha.patil@bharatividyapeeth.edu
Vidya Dodwad - E-mail: vidya.dodwad@bharatividyapeeth.edu
Priyanka Zerwal - E-mail: zerwalpriyanka111@gmail.com
Article Type
Research Article
Date
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract
Antimicrobial photodynamic therapy (aPDT) is a promising non-antibiotic approach for periodontal disinfection, but the efficacy of natural photosensitizers like aloe extract remains underexplored. Therefore, it is of interest to evaluate the antimicrobial efficacy of aloe extract against Porphyromonas gingivalis under varying concentrations and irradiation durations. Results showed significant reductions in bacterial growth, with complete inhibition at 90 seconds of irradiation. The 100 μM/ml concentration demonstrated the highest efficacy at 60 seconds. It enhances understanding by demonstrating the antimicrobial efficacy of aloe extract against Porphyromonas gingivalis under specific conditions, which had not been thoroughly explored before
Keywords
Antimicrobial photodynamic therapy (aPDT); aloe extract; porphyromonas gingivalis; natural photosensitizer; periodontitis
Citation
Naorem et al. Bioinformation 22(3): 1669-1672 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
