Title

Evaluation of oxygen-releasing mouthwash and chlorhexidine as adjuncts in gingivitis treatment: A randomized controlled trial

Authors

Lanka Mahesh^1,*, Meenu Taneja Bhasin² & Nilesh Rathi³

Affiliation

¹Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India; ²Department of Periodontiology, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India; ³Department of Pediatric and Preventive Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India; *Corresponding author

Email

Lanka Mahesh - E-mail: drlanka.mahesh@gmail.com
Meenu Taneja Bhasin - E-mail: drmeenu2005@gmail.com
Nilesh Rathi - E-mail: drnileshrathi@gmail.com

Article Type

Research Article

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

Abstract

Dental biofilm-induced gingivitis can progress to periodontitis without effective plaque control, with chlorhexidine mouthwash often used but causing side effects. Therefore, it is of interest to compare the effectiveness of oxygen-releasing and chlorhexidine mouthwashes as adjuncts to scaling and root planing (SRP). Thirty systemically healthy patients were randomized into two groups, with clinical and microbiological assessments at baseline, 14 and 30 days. Both groups showed significant improvement in clinical parameters and microbial load. The findings advance our knowledge by supporting oxygen-releasing mouthwash as a tolerable alternative to chlorhexidine with similar efficacy.

Keywords

Bleeding on probing (BOP), chlorhexidine, gingival index, oxygen-releasing mouthwash, plaque index

Citation

Mahesh et al. Bioinformation 22(3): 1684-1688 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.