Title
Retinopathy of prematurity: Clinical profiles and risk factors
Authors
Sanskriti Ukey1,*, Ankita Baghel1, Aditi Mishra1, Anamika Dwivedi2 & Sachin Parmar3
Affiliation
1Department of Ophthalmology, Nand Kumar Singh Chauhan Government Medical College, Khandwa, Madhya Pradesh, India; 2Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India; 3Department of Community Medicine, V.K.S. Government Medical College, Neemuch, India; *Corresponding author
Sanskriti Ukey - E-mail: sanskritiukey97@gmail.com
Ankita Baghel - E-mail:
ankibaghel24@gmail.com
Aditi Mishra - E-mail: aditimishra5383@gmail.com
Anamika Dwivedi - E-mail: anamikapgi@gmail.com
Sachin Parmar - E-mail: dr.sachinparmar@gmail.com
Article Type
Research Article
Date
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract
Retinopathy of Prematurity (ROP) is a vasoproliferative retinal disease affecting preterm infants due to abnormal oxygen and growth factor regulation, strongly associated with low birth weight and prematurity. This prospective cohort study conducted at Shyam Shah Medical College, Rewa (September 2022 to February 2024) screened 1188 infants with birth weight <2000g and gestational age <37 weeks for ROP assessment. Of the screened infants, 120 (10.1%) were diagnosed with ROP, with Stage 1 and Zone 1 being most prevalent and multiple pregnancies, low birth weight, small for gestational age and oxygen supplementation identified as significant risk factors. Treatment with anti-VEGF injections and laser therapy achieved favorable outcomes in 96.82% of cases. The study emphasizes that early detection through systematic screening and prompt intervention are critical for preventing severe visual impairment in preterm infants.
Keywords
Retinopathy of Prematurity (ROP), preterm infants, low birth weight, gestational age, Anti-VEGF therapy, screening
Citation
Ukey et al. Bioinformation 22(3): 1779-1783 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
