Title

Ocular ultrasound versus SD-OCT in early papilledema differentiation

Authors

Aditi Mishra^1,*, Sankriti Ukey¹, Ankita Baghel¹, Eva Rani Tirkey² & Sachin Parmar³

Affiliation

¹Department of Ophthalmology, Nand Kumar Singh Chauhan Medical College, Khandwa, Madhya Pradesh, India; ²Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India; ³Department of Community Medicine Department V.K.S. Government Medical College, Neemuch, Madhya Pradesh, India; *Corresponding author

Email

Sanskriti Ukey - E-mail: sanskritiukey97@gmail.com; Phone: +91 9424981755
Ankita Baghel - E-mail: ankibaghel24@gmail.com; Phone: +91 8305948114
Eva Rani Tirkey - E-mail: tirkeyeva652@gmail.com; Phone: +91 9300404990
Sachin Parmar - E-mail: dr.sachinparmar@gmail.com; Phone: +91 9993813103

Aditi Mishra - E-mail: aditimishra5383@gmail.com; Phone: +91 7724845248

Article Type

Research Article

Date

Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026

Abstract

Differentiating early papilledema from pseudopapilledema remains a considerable diagnostic challenge in neuro-ophthalmology due the risks surrounding unnecessary neuroimaging or under-treatment of elevated ICP. Therefore, it is of interest to study of ocular ultrasonography and SD-OCT was carried out in 60 patients with elevation of the optic disc from September 2022 to February 2024. Papilledema was defined as optic nerve sheath diameter >3.3 mm, a positive 30°C test and crescent sign while pseudopapilledema was often associated with hidden disc drusen. SD-OCT had higher sensitivity than ultrasonographic examination (86.7% vs 81.7%) and eyes with papilledema showed thicker peripapillary RNFL, increased ONH volume, decreased GCIPL, enlargement of the blind spot or reduced contrast sensitivity and colour desaturation. The two modalities complement each other - SD-OCT provides quantification and allows differentiation whereas ultrasonography can show anatomical biomarkers, together allowing the early detection of intracranial hypertension as well as avoiding invasive investigations in cases of pseudopapilledema

Keywords

Papilledema, optic disc drusen, tomography, optical coherence.

Citation

Mishra et al. Bioinformation 22(3): 1905-1909 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.