Title
Effect of Drynaria rhizome in-situ gel in periodontitis management
Authors
Kaushal Pati Tripathi1, Neelam Mittal2,*, Anju Gautam1, Aishwarya Pandey1, Sakshi Gupta2 & M. Rashika1
Affiliation
1Department of Periodontology, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India; 2Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India; *Corresponding author
Kaushal Pati Tripathi - E-mail:
jeevankaushal03@gmail.com; Phone: +91 9098925613
Neelam Mittal - E-mail: neelam.mittal@bhu.ac.in; Phone: +91
9415203360
Anju Gautam - E-mail: dranjugautam@bhu.ac.in;
Phone: +91 8299867542
Aishwarya Pandey - E-mail: aishwarya22.ace@gmail.com; Phone: +91
9140120152
Sakshi Gupta - E-mail: dr.sakshibhu@gmail.com; Phone: +91 8004733836
M. Rashika - E-mail: rashika.muralisekar@gmail.com; Phone: +91
7299604333
Article Type
Research Article
Date
Received March 1, 2026; Revised March 31, 2026; Accepted March 31, 2026, Published March 31, 2026
Abstract
The effect of herbal in-situ gel in managing chronic periodontitis is of interest. Therefore, one such herb, Drynaria quercifolia Rhizome in-situ gel was compared with chlorhexidine gel for the treatment of chronic periodontitis. Hence, a total of eighty four sites with probing pockets ≥5 mm were randomly assigned to either gel following scaling or root planing. Clinical parameters-Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD) and Clinical Attachment Level (CAL) were recorded at baseline, 1 month and 2 months. Both groups showed significant improvements, with the Drynaria gel demonstrating greater PPD reduction at 2 months (p < 0.001) despite slightly higher PI and GI scores. No adverse effects were noted, suggesting Drynaria gel is a safe and effective natural adjunct, warranting confirmation in larger, long-term studies.
Keywords
Periodontitis, local drug delivery system (LDDS), Dryanria, herbal gel
Citation
Tripathi et al. Bioinformation 22(3): 1910-1914 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
