Title
Triglyceride glucose index versus triglyceride glucose-BMI index in non-alcoholic fatty liver disease: A correlation with steatosis and fibrosis
Authors
Aditya Joshi1, Deepak Tangadi2 & Ankit Kumar Tiwari3,*
Affiliation
1Department of Medicine, Government Medical College, Jammu, Jammu & Kashmir, India; 2Department of Biochemistry, SSIMS & Research Centre, Davangere, Karnataka, India; 3Department of Biochemistry, Autonomous State Medical College, Kaushambi, Uttar Pradesh, India; *Corresponding author
Aditya Joshi - E-mail: drpu237@gmail.com; Phone: +91 9571648843
Deepak Tangadi - E-mail: deepakstangadi@gmail.com; Phone: +91 9711093963
Ankit Kumar Tiwari - E-mail: biochemistankit@gmail.com; Phone: +91 8601335412
Article Type
Research Article
Date
Received April 1, 2026; Revised April 30, 2026; Accepted April 30, 2026, Published April 30, 2026
Abstract
Non-alcoholic fatty liver disease (NAFLD) links to insulin resistance and cardiometabolic risk, yet cost-effective markers like TyG and TyG-BMI indices for predicting steatosis and fibrosis severity remain under-evaluated in resource-limited settings. This retrospective cross-sectional study at GMC Jammu analyzed 500 NAFLD patients over 1 year, comparing TyG versus TyG-BMI diagnostic value against ultrasonographic steatosis grades and elastographic fibrosis scores using clinical/biochemical records. Both indices rose significantly with advancing steatosis and fibrosis, with TyG-BMI showing stronger correlations with hepatic severity than TyG alone, reflecting the integrated adiposity measures. TyG-BMI demonstrated enhanced predictive performance for NAFLD progression, offering a simple, non-invasive alternative to imaging in high-burden populations. This validates TyG-BMI as a superior, affordable surrogate for risk stratification and NAFLD management in resource-constrained clinical practice.
Keywords
Non-alcoholic fatty liver disease, triglyceride glucose index, BMI index, steatosis
Citation
Joshi et al. Bioinformation 22(4): 2092-2096 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
