Title
Evaluating antibacterial efficiency of orthodontic brackets coated with copper oxide, titanium dioxide and silver nanoparticles
Authors
Girish Polavaram Vasudeva Setty1,*, Shaik Ziauddhin2, Shifin Sainudeen3, Anupriya Boopathy4, Subash Chandra Nayak5, Faraz Hasan6, Rubeena Naaz7 & Md Kafeel Ahmed8
Affiliation
1Private Practitioner, Smile Architect Dental, Bangalore, Karnataka, India; 2Department of Orthodontic and Dentofacial Orthopedics, Coorg Institute of Dental Science, Virajpet, Karnataka, India; 3Private Practitioner, Registrar Orthodontist, Aseer Province, Kingdom of Saudi Arabia; 4Department of Orthodontics and Dentofacial Orthopedics, Sri Venkateshwaraa Dental College, Puducherry, India; 5Department of Orthodontics and Dentofacial Orthopaedics, Hi -Tech Dental College and Hospital, Bhubaneshwar, Odisha, India; 6Department of Orthodontics and Dentofacial Orthopaedics, Consultant Orthodontist, Moradabad Uttar Pradesh, India; 7Private Practitioner, Dental Surgeon, SRK Dental Clinic, Hyderabad, Telangana, India; 8Department of Periodontology and Implantology, MNR Dental College and Hospital, Sangareddy, Hyderabad, Telangana, India; *Corresponding author
Girish Polavaram Vasudeva Setty - E-mail: drgirishpv@gmail.com
Shaik Ziauddhin - E-mail: ziamds.9959505446@gmail.com; Phone: +91 9959505446
Shifin Sainudeen - E-mail: shifin3438@gmail.com
Anupriya Boopathy - E-mail: anupriya@svdcpondy.ac.in
Subash Chandra Nayak - E-mail: drsubashn@gmail.com
Faraz Hasan - E-mail: farazortho@gmail.com
Rubeena Naaz - E-mail: rubeenakhan412@gmail.com
Md Kafeel Ahmed - E-mail: drkafeelsohar@gmail.com
Article Type
Research Article
Date
Received April 1, 2026; Revised April 30, 2026; Accepted April 30,
2026, Published April 30, 2026
Abstract
Orthodontic brackets create biofilm niches that promote enamel demineralization and white spot lesions, necessitating effective antibacterial coatings during fixed appliance therapy. Therefore, it is of interest to compare antibacterial activity against Streptococcus mutans and Lactobacillus acidophilus on 80 brackets coated with CuO-NPs, TiO2-NPs or Ag-NPs versus uncoated controls (n=20/group) using sol-gel dip-coating. All nanoparticle coatings significantly outperformed controls (p<0.001); Ag-NPs showed superior reduction (94.2% S. mutans, 91.8% L. acidophilus), followed by CuO-NPs (87.6%/68.9%) and TiO2-NPs (72.4%/68.9%). SEM/EDX confirmed uniform nanoparticle deposition on bracket surfaces. Thus, Ag-NP coating is the optimal strategy to minimize orthodontic biofilm formation and the risk of demineralization, advancing preventive orthodontics through targeted surface modification.
Keywords
Antibacterial, nanoparticles, orthodontic brackets, silver, copper oxide, titanium dioxide, Streptococcus mutans
Citation
Setty et al. Bioinformation 22(4): 2147-2153 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
