Title
Clinical trial of dental implants in
titanium-zirconium alloy compared to titanium
Authors
Mohamed Amir Khan1, Devarshi Pandya2,*, Koguru Madhavi3, Ratna Rachel Ponraj4, Santanu Mukherjee5, Md Kafeel Ahmed6 & Rubeena Naaz7
Affiliation
1Department of Oral and Maxillofacial Surgery, Registrar Oral and Maxillofacial Surgeon, Buraydah, Kingdom of Saudi Arabia; 2Department of Periodontology, Government Dental College and Hospital, Jamnagar, Gujarat, India; 3Department of Periodontology and Implantology, Consultant, Shine N Smile Advanced Dental Specialty, Hyderabad, Telangana, India; 4Department of Orthodontics and Dentofacial Orthopaedics, Manipal University College Malaysia, Melaka, Malaysia; 5Department of Dentistry, JMN Medical College and Research, Chakdaha, Nadia, West Bengal, India; 6Department of Periodontology and Implantology, MNR Dental College and Hospital, Sangareddy, Hyderabad, Telangana, India; 7Dental Surgeon, SRK Dental Clinic, Hyderabad, Telangana, India; *Corresponding author
Mohamed Amir Khan - E-mail: dramiromfs@gmail.com
Devarshi Pandya - E-mail: devarshi.pandya18@gmail.com
Koguru Madhavi - E-mail: drmadhavi.koguru@gmail.com
Ratna Rachel Ponraj - E-mail: drratnarachelponraj@gmail.com
Santanu Mukherjee - E-mail: santanumukherjee2006@gmail.com
Md Kafeel Ahmed - E-mail: drkafeelsohar@gmail.com
Rubeena Naaz - E-mail: rubeenakhan412@gmail.com
Article Type
Research Article
Date
Received April 1, 2026; Revised April 30, 2026; Accepted April 30, 2026, Published April 30, 2026
Abstract
Titanium dental implants remain the gold standard for oral rehabilitation due to their biocompatibility and osseointegration. Therefore, it is of interest to enhance mechanical strength and stability in low-bone-volume cases where traditional implants may underperform. This randomized clinical trial compared Ti-Zr alloy implants versus conventional pure titanium implants in patients requiring prosthetic rehabilitation, evaluating primary stability, marginal bone loss, peri-implant inflammation and survival rates at regular intervals. Both implant types demonstrated comparable osseointegration rates and overall survival, with standardized clinical assessments conducted throughout the observation period. Ti-Zr implants exhibited superior mechanical stability and better peri- implant bone preservation, particularly in compromised low-density bone sites. Thus, we show Ti-Zr alloy implants as a reliable alternative to conventional titanium, especially for challenging cases requiring enhanced strength and reduced diameters.
Keywords
Dental implants, Titanium-zirconium Alloy (Ti-Zr), osseointegration
Citation
Khan et al. Bioinformation 22(4): 2224-2228 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
